Penicillin allergy: a practical approach to assessment and prescribing.

beta-lactams cephalosporins hypersensitivity

Journal

Australian prescriber
ISSN: 0312-8008
Titre abrégé: Aust Prescr
Pays: Australia
ID NLM: 7804938

Informations de publication

Date de publication:
12 2019
Historique:
entrez: 16 1 2020
pubmed: 16 1 2020
medline: 16 1 2020
Statut: ppublish

Résumé

Penicillin allergies are not always lifelong. Approximately 50% are lost over five years A reaction to penicillin during a childhood infection is unlikely to be a true allergy Only 1–2% of patients with a confirmed penicillin allergy have an allergy to cephalosporins. In patients with a low risk of severe allergic reactions, cephalosporins are a relatively safe treatment option Patients with a history of delayed non-severe reactions, such as mild childhood rashes that occurred over 10 years ago, may be suitable for an oral rechallenge with low-dose penicillin. This should be done in a supervised hospital environment In many cases, with appropriate assessment and allergy testing, it may be possible to remove the penicillin allergy label

Identifiants

pubmed: 31937989
doi: 10.18773/austprescr.2019.065
pii: austprescr-42-192
pmc: PMC6954877
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

192-199

Informations de copyright

(c) NPS MedicineWise 2019.

Déclaration de conflit d'intérêts

Conflicts of interest: none declared

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Auteurs

Misha Devchand (M)

Antimicrobial Stewardship, Drug and Antibiotic Allergy Service and Centre for Antibiotic Allergy and Research, Austin Health, Melbourne.
Pharmacy Department, Austin Health, Melbourne.
The National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne.
Department of Medicine, Austin Health, University of Melbourne.

Jason A Trubiano (JA)

Antimicrobial Stewardship, Drug and Antibiotic Allergy Service and Centre for Antibiotic Allergy and Research, Austin Health, Melbourne.
Pharmacy Department, Austin Health, Melbourne.
The National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne.
Department of Medicine, Austin Health, University of Melbourne.

Classifications MeSH