A Thyroid-stimulating Hormone (TSH) Producing Adenoma in a Patient with Severe Hypothyroidism: Thyroxine Replacement Reduced the TSH Level and Tumor Size.
TRH
TSHoma
primary hypothyroidism
thyroxine
Journal
NMC case report journal
ISSN: 2188-4226
Titre abrégé: NMC Case Rep J
Pays: Japan
ID NLM: 101692589
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
received:
04
01
2019
accepted:
06
06
2019
entrez:
16
1
2020
pubmed:
16
1
2020
medline:
16
1
2020
Statut:
epublish
Résumé
We treated an extremely rare thyroid-stimulating hormone (TSH)-producing pituitary adenoma in a 63-year-old woman with severe hypothyroidism due to autoimmune thyroiditis. She was presented with dizziness and fatigue. The blood level of TSH, prolactin, and fT4 was 288.2 μIU/mL, 72.9 ng/mL, and 0.24 ng/dL, respectively. Magnetic resonance imaging demonstrated a large pituitary tumor, 31 mm in height, and a normal pituitary gland. Preoperative thyroxine replacement reduced the TSH level to 2.05 μIU/mL and produced a significant reduction in the tumor volume. Histopathologically, the surgically removed tumor was a TSH-producing pituitary adenoma.
Identifiants
pubmed: 31938677
doi: 10.2176/nmccrj.cr.2018-0323
pii: nmccrj-7-17
pmc: PMC6957777
doi:
Types de publication
Case Reports
Langues
eng
Pagination
17-21Informations de copyright
© 2020 The Japan Neurosurgical Society.
Déclaration de conflit d'intérêts
Conflicts of Interest Disclosure The authors state that they have no conflict of interest.
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