Localization of ATP-sensitive K

ATP-sensitive K+ channel Hepatic stellate cells Kupffer cells Liver Rat Sinusoidal endothelial cells

Journal

World journal of experimental medicine
ISSN: 2220-315X
Titre abrégé: World J Exp Med
Pays: United States
ID NLM: 101618808

Informations de publication

Date de publication:
19 Dec 2019
Historique:
received: 17 05 2019
revised: 05 09 2019
accepted: 20 11 2019
entrez: 16 1 2020
pubmed: 16 1 2020
medline: 16 1 2020
Statut: epublish

Résumé

ATP-sensitive K To investigate the expression of K Rabbit anti-rat SUR1 peptide antibody was raised and purified by antigen immunoaffinity column chromatography. Four of Sprague-Dawley rats were used for liver protein extraction for immunoblot analysis, seven of them were used for immunohistochemistry both for the ABC method and immunofluorescence staining. Four of Wistar rats were used for the isolation of hepatic stellate cells (HSCs) and Kupffer cells for both primary culture and immunocytochemistry. Immunoblot analysis showed that the five kinds of K Observations from the present study indicated that K

Sections du résumé

BACKGROUND BACKGROUND
ATP-sensitive K
AIM OBJECTIVE
To investigate the expression of K
METHODS METHODS
Rabbit anti-rat SUR1 peptide antibody was raised and purified by antigen immunoaffinity column chromatography. Four of Sprague-Dawley rats were used for liver protein extraction for immunoblot analysis, seven of them were used for immunohistochemistry both for the ABC method and immunofluorescence staining. Four of Wistar rats were used for the isolation of hepatic stellate cells (HSCs) and Kupffer cells for both primary culture and immunocytochemistry.
RESULTS RESULTS
Immunoblot analysis showed that the five kinds of K
CONCLUSION CONCLUSIONS
Observations from the present study indicated that K

Identifiants

pubmed: 31938690
doi: 10.5493/wjem.v9.i2.14
pmc: PMC6955576
doi:

Types de publication

Journal Article

Langues

eng

Pagination

14-31

Informations de copyright

©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: Authors declare no conflicts of interest for this article.

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Auteurs

Ming Zhou (M)

Department of Anatomy, Akita University Graduate School of Medicine, Akita 010-8543, Japan. mzhou@med.akita-u.ac.jp.

Kiwamu Yoshikawa (K)

Department of Cell Biology and Morphology, Akita University Graduate School of Medicine, Akita 010-8543, Japan.

Hideo Akashi (H)

Department of Anatomy, Akita University Graduate School of Medicine, Akita 010-8543, Japan.

Mitsutaka Miura (M)

Department of Cell Biology and Morphology, Akita University Graduate School of Medicine, Akita 010-8543, Japan.

Ryoji Suzuki (R)

Department of Anatomy, Akita University Graduate School of Medicine, Akita 010-8543, Japan.

Tao-Sheng Li (TS)

Department of Stem Cell Biology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki 852-8523, Japan.

Hiroshi Abe (H)

TRUST, A Long-Term Care Health Facility, Sendai 980-0011, Japan.

Yoshio Bando (Y)

Department of Anatomy, Akita University Graduate School of Medicine, Akita 010-8543, Japan.

Classifications MeSH