Obstructive sleep apnea and hypopnea syndrome in patients admitted in a tertiary hospital in Cameroon: Prevalence and associated factors.
Adult
Aged
Body Mass Index
Cameroon
/ epidemiology
Comorbidity
Cross-Sectional Studies
Female
Humans
Hypertension
/ epidemiology
Male
Middle Aged
Polysomnography
/ statistics & numerical data
Prevalence
Risk Factors
Severity of Illness Index
Sleep Apnea, Obstructive
/ diagnosis
Snoring
/ epidemiology
Tertiary Care Centers
/ statistics & numerical data
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2020
2020
Historique:
received:
13
09
2019
accepted:
27
12
2019
entrez:
17
1
2020
pubmed:
17
1
2020
medline:
17
4
2020
Statut:
epublish
Résumé
Obstructive sleep apnea and hypopnea syndrome (OSAHS) is poorly documented in Sub-Saharan Africa, especially in the hospital setting. The aim of this study was to determine its prevalence and to investigate the associated factors in patients admitted in a tertiary referral hospital in Cameroon. In this cross-sectional study conducted in the Cardiology, Endocrinology and Neurology departments of the Yaounde Central Hospital; all patients aged 21 and older were included consecutively. A sample of randomly selected patients was recorded using a portable sleep monitoring device (PMD). OSAHS was defined as apnea-hypopnea index (AHI) ≥ 5/hour (with > 50% of events being obstructive) and moderate to severe OSAHS as an AHI > 15/hour. Logistic regression was used to identify factors associated to OSAHS. Of the 359 patients included, 202 (56.3%) patients were women. The mean age (standard deviation) was 58 (16) years. The prevalence of OSAHS assessed by PMD (95% CI) was 57.7% (48.5-66.9%), 53.8% in men and 62.7% in women (p = 0.44). The median (25th-75th percentiles) AHI, body mass index and Epworth Sleepiness Scale score of OSAHS patients were 17 (10.6-26.9)/hour, 27.4 (24.7-31.6) kg/m2 and 7 (5-9) respectively. The only factor associated to moderate to severe OSAHS was hypertension [odds ratio (95% CI)]: 3.24 (1.08-9.72), p = 0.036. OSAHS is a common condition in patients in this health care centre of Cameroon. In the hospital setting, screening for OSAHS in patients with hypertension is recommended.
Identifiants
pubmed: 31945127
doi: 10.1371/journal.pone.0227778
pii: PONE-D-19-25768
pmc: PMC6964861
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0227778Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Niger Med J. 2014 Jan;55(1):24-8
pubmed: 24970965
Ann Thorac Med. 2014 Apr;9(2):92-8
pubmed: 24791172
BMC Cardiovasc Disord. 2017 May 8;17(1):112
pubmed: 28482815
J Thorac Dis. 2015 Aug;7(8):1311-22
pubmed: 26380759
Lancet. 2005 Mar 19-25;365(9464):1046-53
pubmed: 15781100
J Clin Sleep Med. 2014 Oct 15;10(10):1061-6
pubmed: 25317085
J Diabetes. 2015 Jan;7(1):16-23
pubmed: 24910109
Anesthesiology. 2008 May;108(5):812-21
pubmed: 18431116
Am J Respir Crit Care Med. 2018 Feb 1;197(3):310-312
pubmed: 29035088
Arch Mal Coeur Vaiss. 2007 Aug;100(8):637-41
pubmed: 17928767
Sleep. 1991 Dec;14(6):540-5
pubmed: 1798888
Pneumologie. 1995 Mar;49 Suppl 1:145-7
pubmed: 7617599
Pan Afr Med J. 2012;13:28
pubmed: 23308333
Pan Afr Med J. 2014 Apr 21;17:302
pubmed: 25328598
Chest. 2006 Feb;129(2):238-45
pubmed: 16478837
Ann Cardiol Angeiol (Paris). 2014 Apr;63(2):65-70
pubmed: 24485826
J Clin Sleep Med. 2015 Jul 15;11(7):717-23
pubmed: 25766715
BMC Pulm Med. 2015 Sep 21;15:105
pubmed: 26391008
J Clin Sleep Med. 2009 Jun 15;5(3):263-76
pubmed: 19960649
Sleep Breath. 2012 Sep;16(3):765-71
pubmed: 21904805
Chest. 2014 Nov;146(5):1387-1394
pubmed: 25367475
J Sleep Res. 2019 Oct;28(5):e12770
pubmed: 30272383
Sleep. 2012 Sep 01;35(9):1241-5A
pubmed: 22942502
Sleep Med. 2014 Dec;15(12):1539-46
pubmed: 25308397
PLoS One. 2015 Dec 14;10(12):e0143697
pubmed: 26658438
Lancet Respir Med. 2015 Apr;3(4):310-8
pubmed: 25682233
J Neurol. 2017 Jun;264(6):1247-1253
pubmed: 28550476