Chest CT scoring for evaluation of lung sequelae in congenital diaphragmatic hernia survivors.
CT scoring system
chest CT scan
congenital diaphragmatic hernia
lung disease
pediatric radiology
Journal
Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
11
04
2019
accepted:
27
12
2019
pubmed:
17
1
2020
medline:
25
9
2020
entrez:
17
1
2020
Statut:
ppublish
Résumé
Data on long-term structural lung abnormalities in survivors of congenital diaphragmatic hernia (CDH) is scarce. The purpose of this study was to develop a chest computed tomography (CT) score to assess the structural lung sequelae in CDH survivors and to study the correlation between the CT scoring and clinical parameters in the neonatal period and at 1 year of follow-up. A prospective, clinical follow-up program is organised for CDH survivors at the University Hospital of Leuven including a chest CT at the age of 1 year. The CT scoring used and evaluated, named CDH-CT score, was adapted from the revised Aukland score for chronic lung disease of prematurity. Thirty-five patients were included. All CT scans showed some pulmonary abnormalities, ranging from very mild to severe. The mean total CT score was 16 (IQR: 9-23), with the greatest contribution from the subscores for decreased attenuation (5; IQR: 2-8), subpleural linear and triangular opacities (4; IQR: 3-5), and atelectasis/consolidation (2; IQR: 1-3). Interobserver and intraobserver agreement was very good for the total score (ICC coefficient > 0.9). Total CT score correlated with number of neonatal days ventilated/on oxygen as well as with respiratory symptoms and feeding problems at 1 year of age. The CDH-CT scoring tool has a good intraobserver and interobserver repeatability and correlates with relevant clinical parameters. This holds promise for its use in clinical follow-up and as outcome parameter in clinical interventional studies.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
740-746Informations de copyright
© 2020 Wiley Periodicals, Inc.
Références
Robinson PD, Fitzgerald DA. Congenital diaphragmatic hernia. Paediatr Respir Rev. 2007;8(4):323-335.
van den Hout L, Schaible T, Cohen-Overbeek TE, et al. Actual outcome in infants with congenital diaphragmatic hernia: the role of a standardized postnatal treatment protocol. Fetal Diagn Ther. 2011;29(1):55-63.
Al-Maary J, Eastwood MP, Russo FM, Deprest JA, Keijzer R. Fetal tracheal occlusion for severe pulmonary hypoplasia in isolated congenital diaphragmatic hernia. Ann Surg. 2016;264(6):929-933.
Tracy S, Chen C. Multidisciplinary long-term follow-up of congenital diaphragmatic hernia: a growing trend. Semin Fetal Neonatal Med. 2014;19(6):385-391.
Arena F, Baldari S, Centorrino A, et al. Mid- and long-term effects on pulmonary perfusion, anatomy and diaphragmatic motility in survivors of congenital diaphragmatic hernia. Pediatr Surg Int. 2005;21(12):954-959.
Dotta A, Palamides S, Braguglia A, et al. Lung volumes and distribution of ventilation in survivors to congenital diaphragmatic hernia (CDH) during infancy. Pediatr Pulmonol. 2007;42(7):600-604.
Muratore CS, Kharasch V, Lund DP, et al. Pulmonary morbidity in 100 survivors of congenital diaphragmatic hernia monitored in a multidisciplinary clinic. J Pediatr Surg. 2001;36(1):133-140.
Van Ginderdeuren E, Allegaert K, Decaluwe H, Deprest J, Debeer A, Proesmans M. Clinical outcome for congenital diaphragmatic hernia at the age of 1 year in the era of fetal intervention. Neonatology. 2017;112(4):365-371.
Spoel M, Marshall H, IJsselstijn H, et al. Pulmonary ventilation and micro-structural findings in congenital diaphragmatic hernia. Pediatr Pulmonol. 2016;51(5):517-524.
Tan JK, Banton G, Minutillo C, et al. Long-term medical and psychosocial outcomes in congenital diaphragmatic hernia survivors. Arch Dis Child. 2019;104:761-767.
Aukland SM, Rosendahl K, Owens CM, Fosse KR, Eide GE, Halvorsen T. Neonatal bronchopulmonary dysplasia predicts abnormal pulmonary HRCT scans in long-term survivors of extreme preterm birth. Thorax. 2009;64(5):405-410.
Bhalla M, Turcios N, Aponte V, et al. Cystic fibrosis: scoring system with thin-section CT. Radiology. 1991;179(3):783-788.
Deprest J, Brady P, Nicolaides K, et al. Prenatal management of the fetus with isolated congenital diaphragmatic hernia in the era of the TOTAL trial. Semin Fetal Neonatal Med. 2014;19(6):338-348.
Sarria EE, Mattiello R, Rao L, et al. Quantitative assessment of chronic lung disease of infancy using computed tomography. Eur Respir J. 2012;39(4):992-999.
Calder AD, Bush A, Brody AS, Owens CM. Scoring of chest CT in children with cystic fibrosis: state of the art. Pediatr Radiol. 2014;44(12):1496-1506.
Bagolan P, Morini F. Long-term follow up of infants with congenital diaphragmatic hernia. Semin Pediatr Surg. 2007;16(2):134-144.
Stefanutti G, Filippone M, Tommasoni N, et al. Cardiopulmonary anatomy and function in long-term survivors of mild to moderate congenital diaphragmatic hernia. J Pediatr Surg. 2004;39(4):526-531.
Okuyama H, Kubota A, Kawahara H, Oue T, Kitayama Y, Yagi M. Correlation between lung scintigraphy and long-term outcome in survivors of congenital diaphragmatic hernia. Pediatr Pulmonol. 2006;41(9):882-886.
Weidner M, Zöllner FG, Hagelstein C, et al. High temporal versus high spatial resolution in MR quantitative pulmonary perfusion imaging of two-year old children after congenital diaphragmatic hernia repair. Eur Radiol. 2014;24(10):2427-2434.
Zöllner FG, Zahn K, Schaible T, Schoenberg SO, Schad LR, Neff KW. Quantitative pulmonary perfusion imaging at 3.0 T of 2-year-old children after congenital diaphragmatic hernia repair: initial results. Eur Radiol. 2012;22(12):2743-2749.
Schopper MA, Walkup LL, Tkach JA, et al. Evaluation of neonatal lung volume growth by pulmonary magnetic resonance imaging in patients with congenital diaphragmatic hernia. J Pediatr. 2017;188:96-102.
Kapur S, Bhalla AS, Jana M. Pediatric chest MRI: a review. Indian J Pediatr. 2019;86:842-853.
Mott LS, Graniel KG, Park J, et al. Assessment of early bronchiectasis in young children with cystic fibrosis is dependent on lung volume. Chest. 2013;144(4):1193-1198.
Salamon E, Lever S, Kuo W, Ciet P, Tiddens HAW. Spirometer guided chest imaging in children: it is worth the effort! Pediatr Pulmonol. 2017;52(1):48-56.
Kuo W, Soffers T, Andrinopoulou ER, et al. Quantitative assessment of airway dimensions in young children with cystic fibrosis lung disease using chest computed tomography. Pediatr Pulmonol. 2017;52(11):1414-1423.
Sly PD, Gangell CL, Chen L, et al. Risk factors for bronchiectasis in children with cystic fibrosis. N Engl J Med. 2013;368(21):1963-1970.
Tiddens HAWM, Kuo W, van Straten M, Ciet P. Paediatric lung imaging: the times they are a-changin'. Eur Respir Rev. 2018;27(147):170097.
Rosenow T, Oudraad MCJ, Murray CP, et al. PRAGMA-CF. A quantitative structural lung disease computed tomography outcome in young children with cystic fibrosis. Am J Respir Crit Care Med. 2015;191:1158-1165. https://doi.org/10.1164/rccm.201501-0061OC.