Effects of Capsinoids on Daily Physical Activity, Body Composition and Cold Hypersensitivity in Middle-Aged and Older Adults: A Randomized Study.
Adipose Tissue
/ drug effects
Aged
Aged, 80 and over
Animals
Anti-Inflammatory Agents
/ administration & dosage
Body Composition
/ drug effects
Brain
/ drug effects
Capsicum
Cryopyrin-Associated Periodic Syndromes
/ drug therapy
Double-Blind Method
Energy Metabolism
/ drug effects
Exercise
/ physiology
Female
Humans
Intra-Abdominal Fat
/ drug effects
Japan
Male
Mice
Middle Aged
Plant Extracts
/ administration & dosage
Sedentary Behavior
brain inflammation
brown adipose tissue
capsinoids
chilly sensation
clinical
energy expenditure
energy metabolism
percent body fat
physical activity
visceral fat
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
14 Jan 2020
14 Jan 2020
Historique:
received:
03
12
2019
revised:
05
01
2020
accepted:
09
01
2020
entrez:
18
1
2020
pubmed:
18
1
2020
medline:
12
11
2020
Statut:
epublish
Résumé
Sedentary/inactive lifestyle leads middle-aged and older adults to metabolic syndrome and frailty. Capsinoids from nonpungent chili pepper cultivar have been reported to reduce body fat mass, promote metabolism, and improve unidentified complaints of chills. Additionally, they have an anti-inflammation effect; therefore, we hypothesized that continuous oral ingestion of capsinoids alleviates age-related inflammation in the brain and improves the physical activity (PA) in middle-aged and older adults. In our double-blind human study, 69 participants (17 male, 52 female; mean age: 74.1 ± 7.7 years; range: 52-87 years) were administered either 9 mg of capsinoids which were extracted from pepper fruit variety CH-19 Sweet (
Identifiants
pubmed: 31947529
pii: nu12010212
doi: 10.3390/nu12010212
pmc: PMC7019503
pii:
doi:
Substances chimiques
Anti-Inflammatory Agents
0
Plant Extracts
0
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
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