Gender Differences in Obstructive Sleep Apnea: The Value of Sleep Questionnaires with a Separate Analysis of Cardiovascular Patients.
Athens Insomnia Scale
Berlin
Epworth
Fatigue Scale
Stop Bang
gender
questionnaires
sleep apnea
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
03 Jan 2020
03 Jan 2020
Historique:
received:
24
10
2019
revised:
18
12
2019
accepted:
31
12
2019
entrez:
18
1
2020
pubmed:
18
1
2020
medline:
18
1
2020
Statut:
epublish
Résumé
Gender affects the clinical presentation of obstructive sleep apnea (OSA). The classic OSA symptoms, such as sleepiness, snoring, and apnea, are not so frequent in women. To evaluate possible gender differences in questionnaires used for OSA prediction, such as the Epworth Sleepiness Scale (ESS), STOP, STOP Bang (SB), Berlin Questionnaire (BQ), Athens Insomnia Scale (AIS), and Fatigue Scale (FS). 350 males were matched with 350 women referred to a sleep clinic, according to OSA severity. All responded to the questionnaires and underwent a sleep study. Cardiovascular disease (CVD) patients were separately analyzed. ESS did not differ between genders. SB was higher in males, whereas STOP, BQ, AIS, and FS were higher in females. BQ presented the highest sensitivity in both genders, whereas STOP exhibited the highest specificity in males and ESS in females. AIS and FS were more sensitive and SB more specific in females, whereas BQ was more specific in males. For severe OSA, the predictive values of SB and BQ were almost similar for both genders; however AIS and FS were higher in women. CVD patients presented higher scores, independent of gender, except for AIS, which was higher in females. Gender-specific evaluation of questionnaires is necessary to prevent OSA under-diagnosis.
Sections du résumé
BACKGROUND
BACKGROUND
Gender affects the clinical presentation of obstructive sleep apnea (OSA). The classic OSA symptoms, such as sleepiness, snoring, and apnea, are not so frequent in women.
OBJECTIVES
OBJECTIVE
To evaluate possible gender differences in questionnaires used for OSA prediction, such as the Epworth Sleepiness Scale (ESS), STOP, STOP Bang (SB), Berlin Questionnaire (BQ), Athens Insomnia Scale (AIS), and Fatigue Scale (FS).
METHODS
METHODS
350 males were matched with 350 women referred to a sleep clinic, according to OSA severity. All responded to the questionnaires and underwent a sleep study. Cardiovascular disease (CVD) patients were separately analyzed.
RESULTS
RESULTS
ESS did not differ between genders. SB was higher in males, whereas STOP, BQ, AIS, and FS were higher in females. BQ presented the highest sensitivity in both genders, whereas STOP exhibited the highest specificity in males and ESS in females. AIS and FS were more sensitive and SB more specific in females, whereas BQ was more specific in males. For severe OSA, the predictive values of SB and BQ were almost similar for both genders; however AIS and FS were higher in women. CVD patients presented higher scores, independent of gender, except for AIS, which was higher in females.
CONCLUSION
CONCLUSIONS
Gender-specific evaluation of questionnaires is necessary to prevent OSA under-diagnosis.
Identifiants
pubmed: 31947711
pii: jcm9010130
doi: 10.3390/jcm9010130
pmc: PMC7019723
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Sleep Health. 2019 Oct;5(5):501-508
pubmed: 31302068
Sleep Med. 2016 Oct;26:71-76
pubmed: 27613528
Chest. 2003 May;123(5):1544-50
pubmed: 12740272
Am J Respir Crit Care Med. 2014 Jun 15;189(12):1544-50
pubmed: 24673616
Anesthesiology. 2008 May;108(5):812-21
pubmed: 18431116
Sleep Breath. 2018 Mar;22(1):241-249
pubmed: 28197893
Sleep Med. 2014 Jul;15(7):776-81
pubmed: 24891079
Sleep. 1991 Dec;14(6):540-5
pubmed: 1798888
J Am Heart Assoc. 2018 Jun 21;7(13):
pubmed: 29929990
Obes Surg. 2018 Nov;28(11):3544-3552
pubmed: 30062468
Ann Intern Med. 1999 Oct 5;131(7):485-91
pubmed: 10507956
Sleep. 2004 Mar 15;27(2):305-11
pubmed: 15124727
Am J Respir Crit Care Med. 1994 Mar;149(3 Pt 1):722-6
pubmed: 8118642
Sleep Breath. 2019 Mar;23(1):65-75
pubmed: 29691799
Sleep Breath. 2018 Sep;22(3):683-693
pubmed: 29392572
Can J Anaesth. 2010 May;57(5):423-38
pubmed: 20143278
Sleep Med. 2017 Jul;35:17-22
pubmed: 28619177
Sleep Med. 2009 Dec;10(10):1075-84
pubmed: 19403333
Eur Respir J. 2011 May;37(5):1137-43
pubmed: 20817711
Eur Respir J. 2006 Mar;27(3):564-70
pubmed: 16507857
J Clin Sleep Med. 2011 Oct 15;7(5):467-72
pubmed: 22003341
Circulation. 2016 Nov 1;134(18):e367-e386
pubmed: 27647451
Chest. 2010 Jun;137(6):1449-63
pubmed: 20525657
Anesthesiology. 2009 Apr;110(4):928-39
pubmed: 19293704
Sleep Breath. 2017 Dec;21(4):909-917
pubmed: 28365841
Diabetes Educ. 2005 May-Jun;31(3):401-9
pubmed: 15919640
PLoS One. 2014 Nov 17;9(11):e113076
pubmed: 25402499
J Psychosom Res. 2000 Jun;48(6):555-60
pubmed: 11033374
Multidiscip Respir Med. 2019 Feb 14;14:8
pubmed: 30809382
Obes Surg. 2018 Sep;28(9):2720-2726
pubmed: 29616468
Curr Hypertens Rep. 2014 Oct;16(10):482
pubmed: 25139780
Sleep. 2007 Sep;30(9):1173-80
pubmed: 17910389
Sleep. 2007 Mar;30(3):312-9
pubmed: 17425227
Ann Thorac Med. 2015 Jan-Mar;10(1):25-8
pubmed: 25593603
Sleep Med Rev. 2017 Dec;36:57-70
pubmed: 27919588