Assessing Amphiphilic ABAB Zn(II) Phthalocyanines with Enhanced Photosensitization Abilities in In Vitro Photodynamic Therapy Studies Against Cancer.
ABAB
HeLa
SCC-13
Zn(II) phthalocyanines
amphiphilic
photodynamic therapy
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
04 Jan 2020
04 Jan 2020
Historique:
received:
01
12
2019
revised:
23
12
2019
accepted:
28
12
2019
entrez:
18
1
2020
pubmed:
18
1
2020
medline:
3
11
2020
Statut:
epublish
Résumé
We have previously demonstrated that singlet oxygen photosensitization abilities of Zn(II) phthalocyanines (Zn(II)Pcs) are enhanced through α-functionalization with bulky fluorinated substituents (i.e., bis(trifluoromethyl)phenyl units) at facing positions of ABAB Zn(II)Pcs, where A and B refer to differently functionalized isoindoles. In this work, we have prepared the Zn(II)Pc
Identifiants
pubmed: 31947934
pii: molecules25010213
doi: 10.3390/molecules25010213
pmc: PMC6983099
pii:
doi:
Substances chimiques
Indoles
0
Isoindoles
0
Photosensitizing Agents
0
Singlet Oxygen
17778-80-2
triethylene glycol
3P5SU53360
Polyethylene Glycols
3WJQ0SDW1A
phthalocyanine
V5PUF4VLGY
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Ministerio de Economía, Industria y Competitividad, Gobierno de España
ID : CTQ2017-85393-P and CTQ2016-78454-C2-1-R
Références
Bioconjug Chem. 2012 Nov 21;23(11):2168-72
pubmed: 23057652
Dalton Trans. 2011 Apr 28;40(16):4067-79
pubmed: 21152655
Eur J Med Chem. 2019 May 1;169:53-64
pubmed: 30856406
J Photochem Photobiol B. 2016 Oct;163:385-90
pubmed: 27614847
Photochem Photobiol Sci. 2008 Sep;7(9):1003-10
pubmed: 18754045
Chem Soc Rev. 2009 Feb;38(2):564-84
pubmed: 19169466
Chempluschem. 2019 Jun;84(6):673-679
pubmed: 31944006
Med Sci Monit Basic Res. 2016 Dec 9;22:156-164
pubmed: 27932777
Colloids Surf B Biointerfaces. 2015 Apr 1;128:405-409
pubmed: 25766924
Methods Enzymol. 2000;319:37-49
pubmed: 10907497
Eur J Cell Biol. 2012 Mar;91(3):216-23
pubmed: 22293959
Org Biomol Chem. 2019 Aug 28;17(32):7448-7454
pubmed: 31355402
J Ocul Pharmacol Ther. 2007 Aug;23(4):377-86
pubmed: 17803437
Org Lett. 2014 Sep 19;16(18):4706-9
pubmed: 25181582
Eur J Med Chem. 2020 Feb 1;187:111957
pubmed: 31864170
Photodiagnosis Photodyn Ther. 2019 Mar;25:480-491
pubmed: 30769165
Apoptosis. 2005 Jan;10(1):201-8
pubmed: 15711936
J Biol Inorg Chem. 2019 Mar;24(2):191-210
pubmed: 30673878
Photochem Photobiol Sci. 2009 Mar;8(3):312-8
pubmed: 19255671
Org Biomol Chem. 2008 Dec 21;6(24):4560-6
pubmed: 19039364
Acc Chem Res. 2009 Dec 21;42(12):1910-21
pubmed: 19803479
Dalton Trans. 2015 May 28;44(20):9646-58
pubmed: 25923925
Pharm Res. 2007 Aug;24(8):1405-14
pubmed: 17393074