Prevalence and incidence of bronchiectasis in Italy.
Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Arthritis, Rheumatoid
/ epidemiology
Asthma
/ epidemiology
Bronchiectasis
/ epidemiology
Female
Humans
Incidence
Italy
/ epidemiology
Male
Middle Aged
Prevalence
Primary Health Care
Pulmonary Disease, Chronic Obstructive
/ epidemiology
Sex Distribution
Tuberculosis, Pulmonary
/ epidemiology
Young Adult
Bronchiectasis
Epidemiology
Italy
Journal
BMC pulmonary medicine
ISSN: 1471-2466
Titre abrégé: BMC Pulm Med
Pays: England
ID NLM: 100968563
Informations de publication
Date de publication:
16 Jan 2020
16 Jan 2020
Historique:
received:
04
03
2019
accepted:
07
01
2020
entrez:
18
1
2020
pubmed:
18
1
2020
medline:
20
11
2020
Statut:
epublish
Résumé
The understanding of the epidemiology of bronchiectasis is still affected by major limitations with very few data published worldwide. The aim of this study was to estimate the epidemiological burden of bronchiectasis in Italy in the adult population followed-up by primary care physicians. This study analyzed data coming from a large primary care database with 1,054,376 subjects in the period of time 2002-2015. Patients with bronchiectasis were selected by the use of International Statistical Classification of Diseases, 9th revision, Clinical Modification codes (ICD-9-CM). Patients with bronchiectasis were more likely to have a history of tuberculosis (0.47% vs. 0.06%, p < 0.0001), had higher rates of asthma (16.6% vs. 6.2%, p < 0.0001), COPD (23.3% vs. 6.4%, p < 0.0001) and rheumatoid arthritis (1.9% vs. 0.8%, p < 0.0001). The prevalence and incidence of bronchiectasis in primary care in Italy in 2015 were 163 per 100,000 population and 16.3 per 100,000 person-years, respectively. Prevalence and incidence increased with age and overall rates were highest in men over 75 years old. Prevalence and incidence computed after the exclusion of patients with a diagnosis of either asthma or COPD is 130 per 100,000 and 11.1 cases per 100,000 person-years, respectively. Bronchiectasis is not a rare condition in Italian adult population. Further studies are needed to confirm our results and provide a better insight on etiology of bronchiectasis in Italy. not applicable.
Sections du résumé
BACKGROUND
BACKGROUND
The understanding of the epidemiology of bronchiectasis is still affected by major limitations with very few data published worldwide. The aim of this study was to estimate the epidemiological burden of bronchiectasis in Italy in the adult population followed-up by primary care physicians.
METHODS
METHODS
This study analyzed data coming from a large primary care database with 1,054,376 subjects in the period of time 2002-2015. Patients with bronchiectasis were selected by the use of International Statistical Classification of Diseases, 9th revision, Clinical Modification codes (ICD-9-CM).
RESULTS
RESULTS
Patients with bronchiectasis were more likely to have a history of tuberculosis (0.47% vs. 0.06%, p < 0.0001), had higher rates of asthma (16.6% vs. 6.2%, p < 0.0001), COPD (23.3% vs. 6.4%, p < 0.0001) and rheumatoid arthritis (1.9% vs. 0.8%, p < 0.0001). The prevalence and incidence of bronchiectasis in primary care in Italy in 2015 were 163 per 100,000 population and 16.3 per 100,000 person-years, respectively. Prevalence and incidence increased with age and overall rates were highest in men over 75 years old. Prevalence and incidence computed after the exclusion of patients with a diagnosis of either asthma or COPD is 130 per 100,000 and 11.1 cases per 100,000 person-years, respectively.
CONCLUSIONS
CONCLUSIONS
Bronchiectasis is not a rare condition in Italian adult population. Further studies are needed to confirm our results and provide a better insight on etiology of bronchiectasis in Italy.
TRIAL REGISTRATION
BACKGROUND
not applicable.
Identifiants
pubmed: 31948411
doi: 10.1186/s12890-020-1050-0
pii: 10.1186/s12890-020-1050-0
pmc: PMC6966816
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
15Références
Respir Med. 2019 May;151:121-127
pubmed: 31047108
Respirology. 2016 Nov;21(8):1376-1383
pubmed: 27321896
BMC Pulm Med. 2018 May 22;18(1):83
pubmed: 29788932
Eur Respir J. 2016 Jan;47(1):186-93
pubmed: 26541539
Int J Chron Obstruct Pulmon Dis. 2015 Jul 28;10:1465-75
pubmed: 26251586
Int J Chron Obstruct Pulmon Dis. 2017 May 11;12:1401-1411
pubmed: 28546748
COPD. 2014 Dec;11(6):603-4
pubmed: 25384083
Eur Respir J. 2015 May;45(5):1446-62
pubmed: 25792635
Eur Respir J. 2015 Dec;46(6):1805-7
pubmed: 26293498
PLoS One. 2016 Mar 15;11(3):e0150532
pubmed: 26978269
Chest. 2012 Aug;142(2):432-439
pubmed: 22302301
Eur Respir J. 2009 Oct;34(4):843-9
pubmed: 19357155
Eur Respir J. 2015 Feb;45(2):310-3
pubmed: 25653262
Chron Respir Dis. 2016 Nov;13(4):361-371
pubmed: 27072020
Respiration. 2017;93(3):228-229
pubmed: 28110337
Respir Med. 2016 Dec;121:26-31
pubmed: 27888988