HbA1c levels measured by enzymatic assay during off-site health checkups are lower than those measured by on-site HPLC assay.
Enzymatic assay
HPLC assay
HbA1c
Health checkup
Journal
Diabetology international
ISSN: 2190-1678
Titre abrégé: Diabetol Int
Pays: Japan
ID NLM: 101553224
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
received:
27
06
2019
accepted:
13
08
2019
entrez:
18
1
2020
pubmed:
18
1
2020
medline:
18
1
2020
Statut:
epublish
Résumé
HbA1c is widely used as a therapeutic target marker and as a diagnostic marker for diabetes mellitus. This has led to an increasing frequency of HbA1c measurements in current health checkups throughout Japan. In the present study, we compared the HbA1c levels measured by an enzymatic assay (EA-HbA1c) off-site during health checkups with the HbA1c levels measured by on-site ion-exchange high-performance liquid chromatography (HPLC; HPLC-HbA1c) in a hospital. A total of 96 individuals (53 males and 43 females; age, 68.9 ± 8.4 years old; 70 diabetic and 26 non-diabetic individuals) whose HbA1c levels were measured by both the methods listed above were included in the study. Since no HPLC-HbA1c levels were measured on the day of the health checkup, HPLC-HbA1c levels were estimated using HPLC-HbA1c levels measured before and after the health checkup. A significant correlation of HbA1c levels was observed between the two groups (
Identifiants
pubmed: 31950005
doi: 10.1007/s13340-019-00407-8
pii: 407
pmc: PMC6942106
doi:
Types de publication
Journal Article
Langues
eng
Pagination
67-71Informations de copyright
© The Japan Diabetes Society 2019.
Déclaration de conflit d'intérêts
Conflict of interestThe authors declare that they have no conflicts of interest.
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