Heat shock protein 90 inhibition in the inflamed lungs.
Acute lung injury
Acute respiratory distress syndrome
Inflammation
Journal
Cell stress & chaperones
ISSN: 1466-1268
Titre abrégé: Cell Stress Chaperones
Pays: Netherlands
ID NLM: 9610925
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
12
12
2019
accepted:
08
01
2020
revised:
04
01
2020
pubmed:
18
1
2020
medline:
8
7
2021
entrez:
18
1
2020
Statut:
ppublish
Résumé
Heat shock protein 90 is a highly conserved molecular chaperone, essential for cellular survival under diverse environments. Since this protein is employed by tumors to promote their prevalence, heat shock protein 90 inhibitors have been developed to oppose malignancies. The anti-cancer effects of those compounds appear to be associated with anti-inflammatory properties. Thus, ongoing laborious efforts investigate the possible application of those agents towards inflammatory disorders of the lungs, such as the acute respiratory distress syndrome.
Identifiants
pubmed: 31950341
doi: 10.1007/s12192-020-01069-1
pii: 10.1007/s12192-020-01069-1
pmc: PMC7058811
doi:
Substances chimiques
Anti-Inflammatory Agents
0
HSP90 Heat-Shock Proteins
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
195-197Subventions
Organisme : NIGMS NIH HHS
ID : P20 GM103424
Pays : United States
Références
Lancet Respir Med. 2017 Jun;5(6):524-534
pubmed: 28664851
Cell Stress Chaperones. 2019 Nov;24(6):1027-1044
pubmed: 31734893
Am J Physiol Lung Cell Mol Physiol. 2008 Apr;294(4):L755-63
pubmed: 18245267
Carcinogenesis. 2014 Aug;35(8):1680-90
pubmed: 24942866
Cell Stress Chaperones. 2018 May;23(3):373-384
pubmed: 29067554
Cell Signal. 2020 Mar;67:109500
pubmed: 31837463
Cell Rep. 2018 Mar 27;22(13):3468-3479
pubmed: 29590616
JCI Insight. 2019 Jan 24;4(2):
pubmed: 30674720
J Biochem Mol Toxicol. 2019 Oct;33(10):e22380
pubmed: 31339623
Cytokine. 2019 Jan;113:427-432
pubmed: 30420201
Curr Opin Crit Care. 2019 Feb;25(1):12-20
pubmed: 30531367
Mol Cancer Res. 2015 Nov;13(11):1445-51
pubmed: 26219697
Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L453-66
pubmed: 27343194
Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17037-42
pubmed: 19805107
EBioMedicine. 2018 Nov;37:557-562
pubmed: 30344124
F1000Res. 2019 Nov 22;8:
pubmed: 31824644
FASEB J. 2005 Jun;19(8):1030-2
pubmed: 15811878
Nat Genet. 2004 Jan;36(1):55-62
pubmed: 14702041
Am J Physiol Lung Cell Mol Physiol. 2015 Apr 15;308(8):L776-87
pubmed: 25713322
J Biol Chem. 2004 Nov 19;279(47):48846-54
pubmed: 15358771
Am J Respir Cell Mol Biol. 2008 Nov;39(5):551-9
pubmed: 18474672
Cell Stress Chaperones. 2019 Mar;24(2):309-322
pubmed: 30659446
Nat Rev Dis Primers. 2019 Mar 14;5(1):18
pubmed: 30872586
Biomed Res Int. 2019 Sep 29;2019:1035730
pubmed: 31662961
Biochimie. 2019 Oct;165:206-209
pubmed: 31404589