The Lack of Toxic Effect of High-Power Short-Pulse 101 GHz Millimeter Waves on Healthy Mice.
C57BL/6 mice
millimeter waves
non-thermal irradiation
toxic effect
Journal
Bioelectromagnetics
ISSN: 1521-186X
Titre abrégé: Bioelectromagnetics
Pays: United States
ID NLM: 8008281
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
12
09
2018
accepted:
02
01
2020
pubmed:
18
1
2020
medline:
14
1
2021
entrez:
18
1
2020
Statut:
ppublish
Résumé
Irradiation of cancer cells by non-ionizing millimeter waves (MMW) causes increased cell mortality. We examined if MMW have toxic effects on healthy mice. To that end, the skin of healthy C57BL/6 mice was irradiated locally at the right flank with 101 GHz MMW in a pulsed (5-10 µs) regime using a free electron laser. Irradiation was performed in a dose-dependent manner, with 20-50 pulses and a power range of 0.5-1.5 kW. Physical, physiological, and pathological parameters as well as behavior were examined before and after irradiation. Our results showed that all parameters were within normal range for all experimental mice groups and for the control group. No significant changes were noted in the physical, physiological, or behavioral status of the mice following irradiation as compared with the control group. In addition, no significant changes were found in locomotor, exploratory behavior, or anxiety of the irradiated mice and no pathological changes were noted following the hematological and biochemical blood analysis. Our results indicate that irradiation of healthy mice with MMW does not cause any general toxic effects. Bioelectromagnetics. © 2020 Bioelectromagnetics Society.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
188-199Subventions
Organisme : Ariel Center for Applied Cancer Research grant
ID : Ariel Center for Applied Cancer Research grant
Informations de copyright
© 2020 Bioelectromagnetics Society.
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