Selective Upregulation by Theanine of Slc38a1 Expression in Neural Stem Cell for Brain Wellness.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
15 Jan 2020
Historique:
received: 21 11 2019
revised: 09 01 2020
accepted: 15 01 2020
entrez: 19 1 2020
pubmed: 19 1 2020
medline: 27 10 2020
Statut: epublish

Résumé

Theanine is an amino acid abundant in green tea with an amide moiety analogous to glutamine (GLN) rather than glutamic acid (Glu) and GABA, which are both well-known as amino acid neurotransmitters in the brain. Theanine has no polyphenol and flavonoid structures required for an anti-oxidative property as seen with catechins and tannins, which are more enriched in green tea. We have shown marked inhibition by this exogenous amino acid theanine of the uptake of [

Identifiants

pubmed: 31952134
pii: molecules25020347
doi: 10.3390/molecules25020347
pmc: PMC7024158
pii:
doi:

Substances chimiques

Amino Acid Transport System A 0
Glutamates 0
SLC38A1 protein, human 0
theanine 8021PR16QO

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Yukio Yoneda (Y)

Department of Pharmacology, Osaka University Graduate School of Dentistry, Suita 565-0871, Japan.
The Institute of Prophylactic Pharmacology, Kita-Shinagawa, Shinagawa, Tokyo 140-0001, Japan.

Koichi Kawada (K)

The Institute of Prophylactic Pharmacology, Kita-Shinagawa, Shinagawa, Tokyo 140-0001, Japan.
Department of Pharmacology, Chiba Institute of Science Faculty of Pharmaceutical Sciences, Chiba 288-0025, Japan.

Nobuyuki Kuramoto (N)

The Institute of Prophylactic Pharmacology, Kita-Shinagawa, Shinagawa, Tokyo 140-0001, Japan.
Laboratory of Molecular Pharmacology, Setsunan University Faculty of Pharmaceutical Sciences, Hirakata 573-0101, Japan.

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Classifications MeSH