Creatinine to Body Weight Ratio Is Associated with Incident Diabetes: Population-Based Cohort Study.
creatinine
diabetes
epidemiology
muscle mass
skeletal muscle mass
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
15 Jan 2020
15 Jan 2020
Historique:
received:
13
12
2019
revised:
29
12
2019
accepted:
08
01
2020
entrez:
19
1
2020
pubmed:
19
1
2020
medline:
19
1
2020
Statut:
epublish
Résumé
We investigated the association between creatinine to body weight (Cre/BW) ratio and incident diabetes. In this cohort study, 9659 men and 7417 women were follow up mean (SD) 5.6 (3.5) years and 5.4 (3.4) years, respectively. For men, tertile 1 (T1; n = 3176), Cre/BW < 0.01275; tertile 2 (T2; n = 3258), 0.01275 ≤ Cre/BW < 0.0148; and tertile 3 (T3; n = 3225), Cre/BW ≥ 0.0148; and for women, T1 (n = 2,437), Cre/BMI < 0.0118; T2 (n = 2,516), 0.0118 ≤ Cre/BMI < 0.014; and T3 (n = 2477), Cre/BMI ≥ 0.014. Among them, 362 men and 102 women developed diabetes. The hazard ratios (HRs) of incident diabetes in the T2 group was 0.56 (95% CI 0.44-0.71,
Identifiants
pubmed: 31952309
pii: jcm9010227
doi: 10.3390/jcm9010227
pmc: PMC7020036
pii:
doi:
Types de publication
Journal Article
Langues
eng
Déclaration de conflit d'intérêts
Potential conflicts of interest are as follows: Y.H. has received grant support from Asahi Kasei Pharma. M.F. has received grants, honoraria, and research supports from AstraZeneca plc., Nippon Boehringer Ingelheim Co., Ltd., Sanofi K.K., Daiichi Sankyo Co., Kyowa Hakko Kirin Company Ltd., Kissei Pharmaceutical Co., Ltd., Eli Lilly Japan K.K., Kowa Company, Ltd., Novo Nordisk Pharma Ltd., Sanwa Kagaku Kenkyusho Co., Ltd., Astellas Pharma Inc., MSD K.K., Ltd., Ono Pharmaceutical Co., Ltd., Mitsubishi Tanabe Pharma Corporation, and Takeda Pharmaceutical Co., Ltd. These sponsors were not concerned with this study. The authors and their immediate families have not received any financial payments or other benefits from any commercial entity related to the subject of this article. The authors received no current funding for this study and this does not alter their adherence to all the journal policies on sharing data and materials. The other authors have nothing to disclose.
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