Correlation Between Skeletal Muscle Mass Deficit and Poor Functional Outcome in Patients with Acute Ischemic Stroke.
Age Factors
Aged
Aged, 80 and over
Body Composition
Brain Ischemia
/ complications
Electric Impedance
Female
Geriatric Assessment
Humans
Length of Stay
Male
Middle Aged
Muscle Strength
Muscle, Skeletal
/ physiopathology
Prognosis
Recovery of Function
Risk Factors
Sarcopenia
/ complications
Stroke
/ complications
Stroke Rehabilitation
Time Factors
Bioelectrical impedance analysis
geriatric
outcome
sarcopenia
skeletal muscle mass
stroke
Journal
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
ISSN: 1532-8511
Titre abrégé: J Stroke Cerebrovasc Dis
Pays: United States
ID NLM: 9111633
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
28
08
2019
revised:
28
11
2019
accepted:
22
12
2019
pubmed:
19
1
2020
medline:
21
7
2020
entrez:
19
1
2020
Statut:
ppublish
Résumé
To date, the correlation between sarcopenia, which exists before a stroke, and acute stroke outcome remains partially understood. This study aims to evaluate the skeletal muscle mass deficit using the bioelectrical impedance analysis in patients with acute ischemic stroke. We enrolled 164 geriatric patients with acute ischemic stroke (108 males and 56 females) who underwent the bioelectrical impedance analysis. We evaluated clinical outcomes and their impact on patients with the skeletal muscle mass deficit determined using the skeletal muscle mass index. The skeletal muscle mass deficit was obtained using the bioelectrical impedance analysis in 101 patients. Patients with the skeletal muscle mass deficit determined by the skeletal muscle mass index exhibited severe neurological impairment and functional status on admission; moreover, they tended to display poor functional outcome and prolonged hospital stay. Logistic regression analysis revealed that the skeletal muscle mass deficit remained an independent poor outcome predictor. This study establishes the presence of the skeletal muscle mass deficit in over half patients with acute ischemic stroke. Furthermore, the skeletal muscle mass deficit correlates with neurological impairment owing to stroke with poorer functional prognosis.
Sections du résumé
BACKGROUND AND AIMS
OBJECTIVE
To date, the correlation between sarcopenia, which exists before a stroke, and acute stroke outcome remains partially understood. This study aims to evaluate the skeletal muscle mass deficit using the bioelectrical impedance analysis in patients with acute ischemic stroke.
METHODS
METHODS
We enrolled 164 geriatric patients with acute ischemic stroke (108 males and 56 females) who underwent the bioelectrical impedance analysis. We evaluated clinical outcomes and their impact on patients with the skeletal muscle mass deficit determined using the skeletal muscle mass index.
RESULTS
RESULTS
The skeletal muscle mass deficit was obtained using the bioelectrical impedance analysis in 101 patients. Patients with the skeletal muscle mass deficit determined by the skeletal muscle mass index exhibited severe neurological impairment and functional status on admission; moreover, they tended to display poor functional outcome and prolonged hospital stay. Logistic regression analysis revealed that the skeletal muscle mass deficit remained an independent poor outcome predictor.
CONCLUSIONS
CONCLUSIONS
This study establishes the presence of the skeletal muscle mass deficit in over half patients with acute ischemic stroke. Furthermore, the skeletal muscle mass deficit correlates with neurological impairment owing to stroke with poorer functional prognosis.
Identifiants
pubmed: 31952978
pii: S1052-3057(19)30733-5
doi: 10.1016/j.jstrokecerebrovasdis.2019.104623
pii:
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
104623Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.