Single Dose of Doxycycline for the Prevention of Tick-borne Relapsing Fever.


Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
23 10 2020
Historique:
received: 28 08 2019
accepted: 15 01 2020
pubmed: 20 1 2020
medline: 28 4 2021
entrez: 20 1 2020
Statut: ppublish

Résumé

The current postexposure prophylaxis regimen for tick-borne relapsing fever (TBRF) consists of 5 days' doxycycline. In this observational study of 77 spelunkers at high risk for TBRF, a single dose of 100 mg doxycycline taken up to 72 hours after exposure to ticks was 100% effective in preventing the disease.

Identifiants

pubmed: 31955197
pii: 5709628
doi: 10.1093/cid/ciaa034
doi:

Substances chimiques

Doxycycline N12000U13O

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1768-1771

Informations de copyright

© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Auteurs

Yoav Binenbaum (Y)

Dana Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Laboratory of Pediatric Hemato-Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Ronen Ben-Ami (R)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Infectious Diseases Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Gad Baneth (G)

Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Boaz Langford (B)

Israel Cave Research Center, Institute of Earth Sciences, Hebrew University of Jerusalem, Jerusalem, Israel.

Yoav Negev (Y)

Israel Cave Research Center, Institute of Earth Sciences, Hebrew University of Jerusalem, Jerusalem, Israel.

Edwa Friedlander (E)

Dana Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

David Shasha (D)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Infectious Diseases Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Luba Tau (L)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Infectious Diseases Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Yael Paran (Y)

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Infectious Diseases Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

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Classifications MeSH