Observational study of left ventricular global longitudinal strain in ST-segment elevation myocardial infarction patients with extended pharmaco-invasive strategy: A six months follow-up study.

ST-segment elevation myocardial infarction extended pharmaco-invasive therapy global longitudinal strain left ventricular function percutaneous coronary intervention

Journal

Echocardiography (Mount Kisco, N.Y.)
ISSN: 1540-8175
Titre abrégé: Echocardiography
Pays: United States
ID NLM: 8511187

Informations de publication

Date de publication:
02 2020
Historique:
received: 07 09 2019
revised: 19 12 2019
accepted: 20 12 2019
pubmed: 20 1 2020
medline: 24 6 2021
entrez: 20 1 2020
Statut: ppublish

Résumé

To evaluate left ventricular (LV) function by assessment of LV global longitudinal strain (GLS) in ST-segment elevation myocardial infarction (STEMI) patients who underwent delayed fibrinolysis and coronary intervention (extended pharmaco-invasive strategy), since LV function is one of the determinants of both immediate and long-term outcomes. Prospective study of consecutive STEMI patients who underwent extended pharmaco-invasive strategy. The LV function was estimated using LV GLS at baseline and at 6 months. The study included eighty-seven STEMI patients who received delayed pharmaco-invasive therapy and coronary intervention. The primary aim of the study was to evaluate a change in LV function by assessment of GLS at 6 months as compared to baseline. Prior to PCI, LV ejection fraction was 48.08 ± 6.23% and GLS was -11.11 ± 2.99%. Procedural success was achieved in all patients. LV ejection fraction after 6 months of follow-up increased to 53.12 ± 5.61% and the GLS improved to -13.03 ± 3.06% In comparison to baseline, there was a significant improvement in both LV ejection fraction and GLS at 6 months of follow-up (P < .001).The cardiac mortality was 1.1% at 6 months. There is a significant improvement of LV function as assessed by GLS and ejection fraction at short-term follow-up. In a stable cohort of STEMI patients, extended pharmaco-invasive strategy is also a reasonable option if PCI cannot be performed within the first 24 hours, due to logistic and infrastructural constraints.

Identifiants

pubmed: 31955468
doi: 10.1111/echo.14588
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

283-292

Informations de copyright

© 2020 Wiley Periodicals, Inc.

Références

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Auteurs

Satvic C Manjunath (SC)

Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bengaluru, India.

Balaraju Doddaiah (B)

Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bengaluru, India.

Rajiv Ananthakrishna (R)

Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bengaluru, India.

Sridhar Lakshmana Sastry (SL)

Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bengaluru, India.

Vikram S Patil (VS)

Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bengaluru, India.

Lachikrathman Devegowda (L)

Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bengaluru, India.

Sumangala B Veervhadraiah (SB)

Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bengaluru, India.

Prabhavathi Bhat (P)

Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bengaluru, India.

Cholenahally Nanjappa Manjunath (C)

Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bengaluru, India.

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