Bespoken Nanoceria: An Effective Treatment in Experimental Hepatocellular Carcinoma.
Animals
Apoptosis
/ drug effects
Carcinoma, Hepatocellular
/ drug therapy
Cerium
/ pharmacokinetics
Humans
Lipid Metabolism
/ drug effects
Liver
/ metabolism
Liver Neoplasms, Experimental
/ drug therapy
Male
Nanoparticles
/ therapeutic use
Rats
Rats, Wistar
Signal Transduction
/ drug effects
alpha-Fetoproteins
/ analysis
Journal
Hepatology (Baltimore, Md.)
ISSN: 1527-3350
Titre abrégé: Hepatology
Pays: United States
ID NLM: 8302946
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
received:
26
08
2019
accepted:
20
12
2019
pubmed:
22
1
2020
medline:
4
5
2021
entrez:
22
1
2020
Statut:
ppublish
Résumé
Despite the availability of new-generation drugs, hepatocellular carcinoma (HCC) is still the third most frequent cause of cancer-related deaths worldwide. Cerium oxide nanoparticles (CeO HCC was induced in 110 Wistar rats by intraperitoneal administration of diethylnitrosamine for 16 weeks. Animals were treated with vehicle or CeO These data indicate that CeO
Sections du résumé
BACKGROUND AND AIMS
Despite the availability of new-generation drugs, hepatocellular carcinoma (HCC) is still the third most frequent cause of cancer-related deaths worldwide. Cerium oxide nanoparticles (CeO
APPROACH AND RESULTS
HCC was induced in 110 Wistar rats by intraperitoneal administration of diethylnitrosamine for 16 weeks. Animals were treated with vehicle or CeO
CONCLUSIONS
These data indicate that CeO
Identifiants
pubmed: 31961955
doi: 10.1002/hep.31139
pmc: PMC7702051
doi:
Substances chimiques
alpha-Fetoproteins
0
Cerium
30K4522N6T
ceric oxide
619G5K328Y
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1267-1282Informations de copyright
© 2020 The Authors. Hepatology published by Wiley Periodicals, Inc., on behalf of American Association for the Study of Liver Diseases.
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