Oxidative Stress-Related Gene Polymorphisms Are Associated With Hepatitis B Virus-Induced Liver Disease in the Northern Chinese Han Population.
CYBA
GCLM
NCF4
Nox4
gene polymorphisms
hepatitis B virus
oxidative stress
Journal
Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621
Informations de publication
Date de publication:
2019
2019
Historique:
received:
11
06
2019
accepted:
22
11
2019
entrez:
24
1
2020
pubmed:
24
1
2020
medline:
24
1
2020
Statut:
epublish
Résumé
Oxidative stress is closely related to the occurrence and development of various diseases such as cancer, diabetes, and cardiovascular and infectious diseases. We identified six critical genetic variants related to oxidative stress, and evaluated their main effects and their interaction effects on hepatitis B virus (HBV)-induced liver diseases. We enrolled 3,128 Han Chinese subjects into five groups: healthy controls, chronic hepatitis B (CHB), liver cirrhosis (LC), hepatocellular carcinoma (HCC), and natural clearance. We then determined the genotypes in each group for
Identifiants
pubmed: 31969899
doi: 10.3389/fgene.2019.01290
pmc: PMC6960262
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1290Informations de copyright
Copyright © 2020 Ma, Liu, Zhang, Gao, Yu, Guo, Meng, Gao, Zhou, Yuan, Mi, Zhang, Qi, Li, Wang, Su, Yang and Liu.
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