Torsade de Pointes with severe vitamin D deficiency, an unusual presentation of a common problem.
Prolonged QTc
Torsade de pointes
Vitamin D deficiency
Journal
Journal of cardiology cases
ISSN: 1878-5409
Titre abrégé: J Cardiol Cases
Pays: Japan
ID NLM: 101549579
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
26
04
2019
revised:
15
06
2019
accepted:
07
07
2019
entrez:
24
1
2020
pubmed:
24
1
2020
medline:
24
1
2020
Statut:
epublish
Résumé
Torsade de Pointes (TdP) is a rare cardiac arrhythmia that is associated with prolonged QTc interval. Hypocalcemia is a common cause of prolonged QTc. Although vitamin D deficiency (VDD) is a common disorder in elderly patients with an incidence rate of >40% and can cause hypocalcemia, it has never been linked to TdP. We report a patient with severe VDD that resulted in TdP and cardiac arrest. Post-resuscitation work up illustrated prolonged QTc interval of 620 ms, significant hypocalcemia, and severe VDD of 4 (normal 30-80) ng/mL. After high dose vitamin D/calcium supplements, repeat electrocardiogram revealed normal QTc interval of 423 ms. During hospitalization, the patient suffered no additional arrhythmias and QTc continued to be normal.
Identifiants
pubmed: 31969942
doi: 10.1016/j.jccase.2019.07.003
pii: S1878-5409(19)30057-X
pmc: PMC6962715
doi:
Types de publication
Case Reports
Langues
eng
Pagination
132-134Informations de copyright
© 2019 Published by Elsevier Ltd on behalf of Japanese College of Cardiology.
Références
Cardiol Young. 2015 Feb;25(2):398-9
pubmed: 24820647
J Clin Endocrinol Metab. 2011 Jul;96(7):1911-30
pubmed: 21646368
Am J Cardiol. 2003 Mar 15;91(6):750-2
pubmed: 12633817
Eur Heart J. 2016 May 07;37(18):1456-64
pubmed: 26715165
Can Fam Physician. 2012 Feb;58(2):158-62
pubmed: 22439169
Circulation. 2010 Mar 2;121(8):1047-60
pubmed: 20142454
J Clin Endocrinol Metab. 2008 Oct;93(10):3927-35
pubmed: 18682515
Cardiol Young. 2004 Dec;14(6):667-70
pubmed: 15680004