Peripherally inserted central venous catheter (PICC) in outpatient and inpatient oncological treatment.
Adolescent
Adult
Aged
Catheterization, Central Venous
/ adverse effects
Catheterization, Peripheral
/ adverse effects
Central Venous Catheters
/ adverse effects
Female
Humans
Inpatients
Male
Middle Aged
Neoplasms
/ drug therapy
Outpatients
Prospective Studies
Retrospective Studies
Risk Factors
Young Adult
Complications
Outpatient and inpatient
PICC
Radio-oncology
Journal
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
ISSN: 1433-7339
Titre abrégé: Support Care Cancer
Pays: Germany
ID NLM: 9302957
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
20
06
2019
accepted:
23
12
2019
pubmed:
24
1
2020
medline:
22
10
2020
entrez:
24
1
2020
Statut:
ppublish
Résumé
So far there is little evidence on peripherally inserted central venous catheter (PICC) in radiation oncology patients maintaining the access during the periods of ambulatory and hospital treatment. A total of 522 PICC placements in 484 patients were performed between 11/2011 and 07/2016 at the Department of Radiation Oncology and analysed retrospectively for complications and treatment- and patient-related factors during ambulatory and hospital inpatient use. On initial hospitalization, all patients received a multimodal radio-oncological treatment consisting of radiation and intravenous therapy administered via the PICC. A total of 18,292 catheter days were documented. Median follow-up from catheter insertion to their removal was 37 days (1-97). The overall complication rate was 4.1 per 1000 catheter days (n = 75, 14.4%). Complications were similar between the cohort of outpatient 3.6 per 1000 catheter days and the cohort of inpatient 4.8 per 1000 catheter days (OR 0.976; 95% CI [0.598; 1.619]; p = 0.924). Severe bloodstream infections occurred at a rate of 0.60 per 1000 catheter days (n = 11, 2.1%), deep vein thrombosis at a rate of 0.82 per 1.000 catheter days (n = 15, 2.9%) and local inflammation at a rate of 1.26 per 1.000 catheter days (n = 23, 4.4%). Only immunotherapy could be identified as an independent risk factor for complications (OR 5.6; 95% CI [2.4; 13.1]; p < 0.001). Using PICC in outpatients is not associated with an elevated risk of complications. Particular attention should be payed to early identification of PICC associated bloodstream infections. Immunotherapy is an independent risk factor for local skin complication.
Identifiants
pubmed: 31970514
doi: 10.1007/s00520-019-05276-0
pii: 10.1007/s00520-019-05276-0
pmc: PMC7447660
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4753-4760Références
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