ZnO Modulates Swine Gut Microbiota and Improves Growth Performance of Nursery Pigs When Combined with Peptide Cocktail.
ZnO
growth performance
gut microbiota
nursery pigs
peptide cocktail
Journal
Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893
Informations de publication
Date de publication:
21 Jan 2020
21 Jan 2020
Historique:
received:
04
10
2019
revised:
13
01
2020
accepted:
19
01
2020
entrez:
25
1
2020
pubmed:
25
1
2020
medline:
25
1
2020
Statut:
epublish
Résumé
Zinc has been very efficacious in reducing post-weaning diarrhea, whereas animal-derived peptides are suggested to improve the growth performance of weaned piglets. However, the combined effect of zinc and peptides on swine production and swine gut microbiota is still largely unknown. In this study, we followed 288 nursery pigs from the age of d30 to d60 to evaluate the growth performance and gut microbiota of weanling pigs subjected to different levels of a fish-porcine-microbial peptide cocktail (0.05%, 0.25%, and 0.5%) with or without the pharmaceutical level of zinc oxide (ZnO) (2500 ppm) supplementation in a nutrient-deficient diet. Rectal swab samples were collected from pigs with body weight (BW) approach average at each pen on d30, d42, and d60 to determine gut microbiota. Average daily gain (ADG) and BW in piglets fed high zinc (HZ) increased with increasing levels of peptide. The microbiota of the HZ group also diverged from those of the standard zinc (SZ) group from d30 to d60. Adding peptide did not alter community structure regardless of zinc supplementation. Collectively, these findings demonstrated that the pharmaceutical level of zinc as ZnO conditioned the gut community to the point where peptide could effectively restore growth performance in nursery pigs fed nutrient-deficient diets.
Identifiants
pubmed: 31973057
pii: microorganisms8020146
doi: 10.3390/microorganisms8020146
pmc: PMC7074828
pii:
doi:
Types de publication
Journal Article
Langues
eng
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Appl Environ Microbiol. 2005 May;71(5):2267-77
pubmed: 15870311
Gut. 2003 Mar;52(3):439-51
pubmed: 12584232
J Nutr. 2003 Dec;133(12):4077-82
pubmed: 14652351
Appl Environ Microbiol. 2013 Sep;79(17):5112-20
pubmed: 23793624
J Int Med Res. 2016 Apr;44(2):377-88
pubmed: 26857859
J Nutr. 2001 May;131(5):1520-7
pubmed: 11340110
Front Microbiol. 2018 Nov 29;9:2889
pubmed: 30555436
Restor Dent Endod. 2014 May;39(2):109-14
pubmed: 24790923
Res Vet Sci. 2006 Feb;80(1):45-54
pubmed: 15946717
J Am Coll Nutr. 2007 Dec;26(6):679S-83S
pubmed: 18187433
Comp Biochem Physiol Comp Physiol. 1992 Sep;103(1):189-97
pubmed: 1356696
Am J Cardiol. 2010 Aug 15;106(4):470-6
pubmed: 20691303
J Nutr Sci Vitaminol (Tokyo). 2003 Dec;49(6):414-21
pubmed: 14974732
Appl Environ Microbiol. 2011 Apr;77(7):2325-31
pubmed: 21296935
Microbes Environ. 2017 Dec 27;32(4):300-313
pubmed: 29129876
Environ Microbiol. 2006 Jul;8(7):1191-9
pubmed: 16817927
Anim Biotechnol. 2006;17(2):207-15
pubmed: 17127531
Appl Environ Microbiol. 2009 Dec;75(23):7537-41
pubmed: 19801464
Br J Nutr. 1963;17:141-50
pubmed: 14021819
Appl Environ Microbiol. 2014 Feb;80(3):928-34
pubmed: 24271166
Int Arch Med. 2012 Jan 26;5(1):2
pubmed: 22281066
PLoS One. 2014 Nov 17;9(11):e111289
pubmed: 25402188
J Am Assoc Nurse Pract. 2016 Aug;28(8):410-4
pubmed: 27092809
Nat Rev Neurosci. 2012 Oct;13(10):701-12
pubmed: 22968153
Front Microbiol. 2018 Sep 07;9:1798
pubmed: 30245669
Urol Oncol. 2017 Apr;35(4):135-141
pubmed: 28233671
Biomed Res Int. 2014;2014:608979
pubmed: 24527452
J Clin Diagn Res. 2017 May;11(5):CC01-CC04
pubmed: 28658752
Sci Rep. 2018 Apr 13;8(1):5985
pubmed: 29654314
J Immunol Res. 2016;2016:1469780
pubmed: 27006954
Am J Clin Nutr. 1998 Aug;68(2 Suppl):447S-463S
pubmed: 9701160
Br J Nutr. 2013 Aug;110(4):681-8
pubmed: 23308387
Poult Sci. 2014 Feb;93(2):400-11
pubmed: 24570462
J Nutr. 2004 Sep;134(9):2256-62
pubmed: 15333713
Dig Dis Sci. 1981 Feb;26(2):100-6
pubmed: 7460712
Gut. 2005 Jun;54(6):775-81
pubmed: 15888784
Appl Environ Microbiol. 2004 Oct;70(10):5810-7
pubmed: 15466518
FEMS Microbiol Ecol. 2014 Feb;87(2):416-27
pubmed: 24118028
Anim Sci J. 2009 Oct;80(5):556-61
pubmed: 20163620
Biol Psychiatry. 2009 Oct 1;66(7):627-35
pubmed: 19423077
Front Microbiol. 2017 Jun 02;8:992
pubmed: 28626453
J Nutr. 2003 Oct;133(10):3187-90
pubmed: 14519808
World J Surg. 2008 Aug;32(8):1757-62
pubmed: 18340479
Curr Opin Clin Nutr Metab Care. 2007 Sep;10(5):632-8
pubmed: 17693749
J Pediatr Gastroenterol Nutr. 1998 Apr;26(4):446-53
pubmed: 9552143
Comp Biochem Physiol A Mol Integr Physiol. 2000 Apr;125(4):525-31
pubmed: 10840229
Microbiome. 2019 Jul 30;7(1):109
pubmed: 31362781
Am J Clin Nutr. 1991 Feb;53(2):403-12
pubmed: 1989405
Pediatrics. 2007 Jun;119(6):1120-30
pubmed: 17545379
Foodborne Pathog Dis. 2013 Apr;10(4):331-7
pubmed: 23461609
J Pediatr Gastroenterol Nutr. 2009 Jul;49(1):23-30
pubmed: 19465870
J Nutr Biochem. 2007 Dec;18(12):820-6
pubmed: 17475461
J Anim Physiol Anim Nutr (Berl). 2019 Jan;103(1):231-241
pubmed: 30298533
J Anim Sci. 1993 Nov;71(11):3020-4
pubmed: 8270523
J Anim Sci. 1997 Jul;75(7):1861-6
pubmed: 9222843
Proc Nutr Soc. 2013 Feb;72(1):173-7
pubmed: 23146206
J Appl Microbiol. 2006 Jun;100(6):1171-85
pubmed: 16696665
Innate Immun. 2014 Jul;20(5):478-86
pubmed: 23956359
Psychiatry Res. 2019 Jan;271:8-14
pubmed: 30448449