A lysosomal K

Animals Calcium / metabolism Cell Line Large-Conductance Calcium-Activated Potassium Channels / genetics Lysosomes / metabolism Macrophages / metabolism Mice Mice, Knockout Microspheres Phagocytosis / physiology RAW 264.7 Cells Synaptotagmins / metabolism Transient Receptor Potential Channels / genetics

Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
23 01 2020
Historique:
received: 24 07 2019
accepted: 31 12 2019
entrez: 25 1 2020
pubmed: 25 1 2020
medline: 11 11 2020
Statut: epublish

Résumé

Macrophages are highly specialized in removing large particles including dead cells and cellular debris. When stimulated, delivery of the intracellular lysosomal membranes is required for the formation of plasmalemmal pseudopods and phagosomes. As a key lysosomal Ca

Identifiants

DOI: 10.1038/s41598-020-57874-2 PMID: 31974459 PMC: PMC6978423
pubmed: 31974459
doi: 10.1038/s41598-020-57874-2
pii: 10.1038/s41598-020-57874-2
pmc: PMC6978423
doi:

Substances chimiques

Large-Conductance Calcium-Activated Potassium Channels 0
Mcoln1 protein, mouse 0
Transient Receptor Potential Channels 0
Synaptotagmins 134193-27-4
Calcium SY7Q814VUP

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1038

Subventions

Organisme : CIHR
ID : MOP-119349
Pays : Canada

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Auteurs

Xue Sun (X)

Key Laboratory of Molecular Epigenetics of Ministry of Education, Institute of Cytology and Genetics, Northeast Normal University, Changchun, Jilin, China.
Department of Physiology and Biophysics, Dalhousie University, Sir Charles Tupper Medical Building, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada.

Mengnan Xu (M)

Department of Physiology and Biophysics, Dalhousie University, Sir Charles Tupper Medical Building, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada.

Qi Cao (Q)

Department of Physiology and Biophysics, Dalhousie University, Sir Charles Tupper Medical Building, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada.

Peng Huang (P)

Collaborative Innovation Center for Biomedicine, School of Clinical Medicine, Shanghai University of Medicine and Health Sciences, 279 Zhouzhu Rd, Shanghai, 201318, China. huangp320@sina.com.

Xiaojuan Zhu (X)

Key Laboratory of Molecular Epigenetics of Ministry of Education, Institute of Cytology and Genetics, Northeast Normal University, Changchun, Jilin, China. zhuxj720@nenu.edu.cn.

Xian-Ping Dong (XP)

Department of Physiology and Biophysics, Dalhousie University, Sir Charles Tupper Medical Building, 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada. xpdong@dal.ca.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › A lysosomal K
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Calcium › A lysosomal K
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › A lysosomal K
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux potassiques › Canaux potassiques calcium-dépendants › Canaux potassiques calcium-dépendants de grande conductance › A lysosomal K
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Lysosomes › A lysosomal K
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Macrophages › A lysosomal K
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › A lysosomal K
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › A lysosomal K
questionsmedicales.fr › Équipement et fournitures › Microsphères › A lysosomal K
questionsmedicales.fr › Phénomènes du système immunitaire › Phagocytose › A lysosomal K
questionsmedicales.fr › Cellules › Cellules RAW 264.7 › A lysosomal K
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines du transport vésiculaire › Synaptotagmines › A lysosomal K
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux cationiques TRP › A lysosomal K