Review of Preferential Suspicious Genes in Microtia Patients Through Various Approaches.
Journal
The Journal of craniofacial surgery
ISSN: 1536-3732
Titre abrégé: J Craniofac Surg
Pays: United States
ID NLM: 9010410
Informations de publication
Date de publication:
Historique:
pubmed:
25
1
2020
medline:
15
7
2020
entrez:
25
1
2020
Statut:
ppublish
Résumé
Recently, an increasing trend of the birth prevalence of anotia/microtia is observed in China, contributed by changes of social environment and lifestyle. There seems to be no major breakthroughs in exact pathogenesis of microtia, though the research results related to molecular genetics unceasingly appear. In this review, the authors focus on the results of various research methods which the authors regard as the preferential suspicious gene pool to facilitate the exploration of the pathogenic genes of microtia, knowing that the mechanism of microtia is very complicated. The advantages and limitations of these various approaches will also be systematically delineated. The authors believe that this review will give a deep insight in the genetic research of microtia and help plastic surgeons manage congenital microtia more effectively.
Identifiants
pubmed: 31977690
doi: 10.1097/SCS.0000000000006244
pii: 00001665-202004000-00057
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
538-541Références
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