CD44 Targeting Mediated by Polymeric Nanoparticles and Combination of Chlorine TPCS
cancer stem cells
chemotherapy
combination therapy
hyaluronic acid
mammospheres
photodynamic therapy
targeted nanoparticles
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
23 Jan 2020
23 Jan 2020
Historique:
received:
05
11
2019
revised:
09
01
2020
accepted:
21
01
2020
entrez:
26
1
2020
pubmed:
26
1
2020
medline:
26
1
2020
Statut:
epublish
Résumé
The presence of rare but highly tumorigenic cancer stem cells (CSCs) within the tumors is recognized as one of the major reasons of failure of conventional chemotherapies, mainly attributed to the development of drug resistance and increasing metastatic potential. Here, we propose a therapeutic strategy based on the simultaneous delivery of docetaxel (DTX) and the photosensitizer meso-tetraphenyl chlorine disulfonate (TPCS
Identifiants
pubmed: 31979218
pii: cancers12020278
doi: 10.3390/cancers12020278
pmc: PMC7072409
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Associazione Italiana per la Ricerca sul Cancro
ID : IG2014 #15764
Organisme : Department of Biology, University of Padova
ID : PRIDseed2018
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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