[Enteroviral infections in adults treated with rituximab: A new case of chronic meningitis and myofasciitis and literature review].
Infections à entérovirus de l’adulte traité par rituximab : un nouveau cas de méningite et myofasciite chronique et revue de la littérature.
Adult
Agammaglobulinemia
/ chemically induced
Chronic Disease
Enterovirus Infections
/ chemically induced
Fasciitis
/ chemically induced
Female
France
Humans
Immunoglobulins, Intravenous
/ therapeutic use
Meningitis
/ chemically induced
Myositis
/ chemically induced
Purpura, Thrombocytopenic, Idiopathic
/ drug therapy
Rituximab
/ adverse effects
Enterovirus
Entérovirus
Hypogammaglobulinemia
Hypogammaglobulinémie
Meningitis
Myofasciite
Myofasciitis
Méningite
Rituximab
Journal
La Revue de medecine interne
ISSN: 1768-3122
Titre abrégé: Rev Med Interne
Pays: France
ID NLM: 8101383
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
06
09
2019
revised:
07
12
2019
accepted:
23
12
2019
pubmed:
26
1
2020
medline:
15
12
2020
entrez:
26
1
2020
Statut:
ppublish
Résumé
Chronic enterovirus infections can occur in primary immunodeficiency with hypogammaglobulinemia. They usually associate meningitis and myofasciitis. Such infections have also been described in adults with rituximab-induced hypogammaglobulinemia. We report the case of a 33-year-old woman who was given rituximab for immune thrombocytopenia and developed rituximab-induced hypogammaglobulinemia (IgG 4.4g/L). One year after the last rituximab infusion, she developed lower limbs myofasciitis, followed two months later by a chronic lymphocytic meningitis. PCR in the serum and the cerebrospinal fluid at the time of the meningitis and the myofasciitis were positive to the same enterovirus (echovirus 11) while it was negative in the fascia biopsy. Under treatment with intravenous immunoglobulins, all symptoms and laboratory abnormalities improved and enterovirus PCR became negative. We report a case of chronic enterovirus infection associating meningitis and myofasciitis in an adult with rituximab-induced hypogammaglobulinemia. Outcome was favorable under treatment with intravenous immunoglobulins.
Identifiants
pubmed: 31980187
pii: S0248-8663(20)30006-0
doi: 10.1016/j.revmed.2019.12.018
pii:
doi:
Substances chimiques
Immunoglobulins, Intravenous
0
Rituximab
4F4X42SYQ6
Types de publication
Case Reports
Journal Article
Review
Langues
fre
Sous-ensembles de citation
IM
Pagination
200-205Informations de copyright
Copyright © 2020 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.