Viewing Nuclear Architecture through the Eyes of Nocturnal Mammals.
Journal
Trends in cell biology
ISSN: 1879-3088
Titre abrégé: Trends Cell Biol
Pays: England
ID NLM: 9200566
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
received:
11
10
2019
revised:
10
12
2019
accepted:
19
12
2019
pubmed:
26
1
2020
medline:
25
6
2021
entrez:
26
1
2020
Statut:
ppublish
Résumé
The cell nucleus is a remarkably well-organized organelle with membraneless but distinct compartments of various functions. The largest of them, euchromatin and heterochromatin, are spatially segregated in such a way that the transcriptionally active genome occupies the nuclear interior, whereas silent genomic loci are preferentially associated with the nuclear envelope. This rule is broken by rod photoreceptor cells of nocturnal mammals, in which the two major compartments have inverted positions. The inversion and dense compaction of heterochromatin converts these nuclei into microlenses that focus light and facilitate nocturnal vision. As is often the case in biology, when a mutation helps to understand normal processes and structures, inverted nuclei have served as a tool to unravel general principles of nuclear organization, including mechanisms of heterochromatin tethering to the nuclear envelope, autonomous behavior of small genomic segments, and euchromatin-heterochromatin segregation.
Identifiants
pubmed: 31980345
pii: S0962-8924(19)30222-3
doi: 10.1016/j.tcb.2019.12.008
pmc: PMC7293902
mid: NIHMS1569406
pii:
doi:
Substances chimiques
Heterochromatin
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
276-289Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM114190
Pays : United States
Organisme : NIDDK NIH HHS
ID : U54 DK107980
Pays : United States
Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.
Références
Genes Dev. 2019 Feb 1;33(3-4):144-149
pubmed: 30692205
Cell. 2018 Dec 13;175(7):1842-1855.e16
pubmed: 30449618
Cell. 2017 Oct 19;171(3):557-572.e24
pubmed: 29053968
PLoS Comput Biol. 2008 Aug 22;4(8):e1000153
pubmed: 18725929
Genome Res. 2017 Jun;27(6):922-933
pubmed: 28341771
Genes (Basel). 2011 Aug 02;2(3):502-15
pubmed: 24710208
Cell. 2012 Aug 31;150(5):934-47
pubmed: 22939621
Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):4672-7
pubmed: 25825760
Science. 2009 Oct 9;326(5950):289-93
pubmed: 19815776
Nature. 2019 Aug;572(7770):543-548
pubmed: 31391587
Biophys J. 2018 May 22;114(10):2262-2270
pubmed: 29628210
Opt Lett. 2010 Aug 1;35(15):2639-41
pubmed: 20680084
EMBO Rep. 2016 Feb;17(2):139-55
pubmed: 26792937
Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2782-7
pubmed: 24550308
Nature. 2017 Jul 13;547(7662):241-245
pubmed: 28636597
Cell. 2009 Apr 17;137(2):356-68
pubmed: 19379699
Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E7987-E7996
pubmed: 30072429
Science. 2018 Jul 27;361(6400):
pubmed: 29930091
Cell. 2013 Jan 31;152(3):584-98
pubmed: 23374351
Histochem Cell Biol. 2016 Apr;145(4):359-72
pubmed: 26847178
Nat Rev Mol Cell Biol. 2017 Oct;18(10):637-650
pubmed: 28792005
Science. 2017 Jul 28;357(6349):
pubmed: 28751582
Genome Res. 2019 Aug;29(8):1235-1249
pubmed: 31201210
Mol Cell. 2019 Oct 17;76(2):306-319
pubmed: 31521504
Carcinogenesis. 2015 Nov;36(11):1263-74
pubmed: 26354777
Cell. 2018 Jul 26;174(3):744-757.e24
pubmed: 29887377
Genome Res. 2017 Oct;27(10):1634-1644
pubmed: 28916540
Curr Biol. 2007 Mar 6;17(5):R161-3
pubmed: 17339011
Science. 2018 Aug 31;361(6405):924-928
pubmed: 30166492
Elife. 2016 Mar 07;5:e11613
pubmed: 26949250
Genome Biol. 2015 Aug 10;16:154
pubmed: 26257189
Nat Rev Mol Cell Biol. 2017 May;18(5):285-298
pubmed: 28225081
Nature. 2017 Jul 13;547(7662):236-240
pubmed: 28636604
Curr Biol. 2005 Oct 11;15(19):R794-6
pubmed: 16213808
Nature. 2019 Jun;570(7761):395-399
pubmed: 31168090
Genome Biol. 2013 Feb 15;14(2):R14
pubmed: 23414781
Genome Res. 2013 Feb;23(2):270-80
pubmed: 23124521
J Cell Biol. 2018 Nov 5;217(11):4025-4048
pubmed: 30154186
Chromosome Res. 2013 Aug;21(5):535-54
pubmed: 23996328
Differentiation. 2017 Mar - Apr;94:58-70
pubmed: 28056360
Annu Rev Biophys. 2010;39:471-89
pubmed: 20462379
J Mol Biol. 1961 Dec;3:711-6
pubmed: 14456492
J Mol Biol. 2020 Feb 7;432(3):676-681
pubmed: 31689436
Nat Rev Mol Cell Biol. 2019 Jun;20(6):327-337
pubmed: 30886333
Nat Struct Mol Biol. 2019 Apr;26(4):297-307
pubmed: 30936528
Cell Rep. 2015 Feb 3;10(4):471-83
pubmed: 25640177
Science. 2018 Jul 27;361(6400):412-415
pubmed: 29930094
Biochemistry. 2018 May 1;57(17):2540-2548
pubmed: 29644850
Nature. 2008 Jun 12;453(7197):948-51
pubmed: 18463634
Elife. 2019 Dec 11;8:
pubmed: 31825309
Biochem Soc Trans. 2011 Dec;39(6):1735-41
pubmed: 22103517
Nat Rev Genet. 2017 Aug;18(8):457-472
pubmed: 28529337
Nature. 2019 Jul;571(7765):424-428
pubmed: 31292544
Chromosome Res. 2001;9(7):541-67
pubmed: 11721953
Curr Opin Genet Dev. 2019 Apr;55:106-113
pubmed: 31491591
Curr Opin Cell Biol. 2016 Jun;40:47-59
pubmed: 26938331
Cell. 2013 Mar 28;153(1):178-92
pubmed: 23523135
J Cell Biol. 1999 Feb 22;144(4):617-29
pubmed: 10037785
Cell. 2015 Nov 5;163(4):934-46
pubmed: 26544940
Curr Opin Genet Dev. 2007 Oct;17(5):435-42
pubmed: 17905579
J Cell Biol. 2013 Dec 9;203(5):767-83
pubmed: 24297746
Mol Cell. 2019 Aug 8;75(3):549-561.e7
pubmed: 31398323
Nat Biotechnol. 2000 Apr;18(4):424-8
pubmed: 10748524
Nature. 2017 Apr 6;544(7648):110-114
pubmed: 28355183
Nature. 2017 Jul 12;547(7662):232-235
pubmed: 28703188
Nucleic Acids Res. 2012 Dec;40(22):11477-89
pubmed: 23066103
Chem Rev. 2013 Nov 13;113(11):8683-705
pubmed: 23597155
Annu Rev Cell Dev Biol. 2014;30:39-58
pubmed: 25288112
PLoS Genet. 2010 Mar 26;6(3):e1000889
pubmed: 20361057
Cytogenet Genome Res. 2015;147(4):217-39
pubmed: 26967166
Cell Rep. 2017 Feb 7;18(6):1366-1382
pubmed: 28178516
Nat Rev Genet. 2018 Dec;19(12):789-800
pubmed: 30367165
Nature. 1984 Mar 29-Apr 4;308(5958):414-21
pubmed: 6424026
Trends Biochem Sci. 2018 Jun;43(6):469-478
pubmed: 29685368
Mol Cell. 2016 Jun 16;62(6):834-847
pubmed: 27264872
Sci Rep. 2017 Mar 03;7:43184
pubmed: 28256534
Mol Cell. 2010 May 28;38(4):603-13
pubmed: 20513434
Curr Biol. 2014 May 19;24(10):1080-90
pubmed: 24794298
Elife. 2017 Aug 01;6:
pubmed: 28760199
Curr Opin Cell Biol. 2019 Jun;58:142-152
pubmed: 31228682
Nucleic Acids Res. 2016 May 5;44(8):3503-12
pubmed: 27060145
Nature. 2013 Oct 3;502(7469):59-64
pubmed: 24067610
Nucleus. 2013 Nov-Dec;4(6):460-77
pubmed: 24213376
J Cell Biol. 2009 Apr 6;185(1):87-100
pubmed: 19349581
Cell. 2017 May 18;169(5):780-791
pubmed: 28525751
Cell. 2012 Nov 9;151(4):724-737
pubmed: 23141535
Nat Rev Mol Cell Biol. 2019 Sep;20(9):535-550
pubmed: 31197269
Curr Biol. 2006 Jul 11;16(13):R484-9
pubmed: 16824904
PLoS One. 2008 Feb 20;3(2):e1661
pubmed: 18286208
Cell. 2013 Mar 14;152(6):1355-64
pubmed: 23498942
EMBO Rep. 2019 May;20(5):
pubmed: 30858340
Genome Biol. 2018 Aug 24;19(1):125
pubmed: 30143029
Curr Opin Genet Dev. 2013 Apr;23(2):191-6
pubmed: 23415810
Nat Genet. 2019 Oct;51(10):1442-1449
pubmed: 31501517
Genomics. 1989 Oct;5(3):407-14
pubmed: 2613229
Cold Spring Harb Perspect Biol. 2011 Mar 01;3(3):
pubmed: 21106648
Cell. 2015 Sep 24;163(1):134-47
pubmed: 26365489
Trends Genet. 2019 Feb;35(2):89-92
pubmed: 30477958
Chromosoma. 2018 Jun;127(2):175-186
pubmed: 29322240
Nat Rev Genet. 2019 Aug;20(8):437-455
pubmed: 31086298
Cell. 2017 Mar 23;169(1):13-23
pubmed: 28340338
J Cell Biol. 1999 Jun 14;145(6):1119-31
pubmed: 10366586
Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1460-E1469
pubmed: 28179571
Curr Opin Genet Dev. 2019 Apr;55:19-25
pubmed: 31112905