Meroterpenoid pyrones, alkaloid and bicyclic brasiliamide from the fungus Neosartorya hiratsukae.


Journal

Fitoterapia
ISSN: 1873-6971
Titre abrégé: Fitoterapia
Pays: Netherlands
ID NLM: 16930290R

Informations de publication

Date de publication:
Apr 2020
Historique:
received: 18 11 2019
revised: 17 01 2020
accepted: 22 01 2020
pubmed: 27 1 2020
medline: 15 12 2020
entrez: 27 1 2020
Statut: ppublish

Résumé

Two new meroterpenoid pyrones, chevalone G (1) and aszonapyrone C (2), a new indole alkaloid, 7-chlorofischerindoline (3) and a new bicyclic brasiliamide, brasiliamide H (4), together with sixteen known compounds, 5-20 were isolated from the fungus Neosartorya hiratsukae. Their structures were established on the basis of spectroscopic evidence. The antibacterial activity and the cytotoxic activity of new compounds were evaluated.

Identifiants

pubmed: 31982554
pii: S0367-326X(20)30067-8
doi: 10.1016/j.fitote.2020.104485
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Antineoplastic Agents 0
Pyrones 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

104485

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest All the authors declare that there is no conflict of interest concerning this work.

Auteurs

Jakkapat Paluka (J)

Natural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.

Kwanjai Kanokmedhakul (K)

Natural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.

Mayamor Soytong (M)

Department of Biology, Faculty of Science, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand.

Kasem Soytong (K)

Department of Plant Pest Management, Faculty of Agricultural Technology, King Mongkut's Institute of Technology Ladkrabang, Ladkrabang, Bangkok 10520, Thailand.

Jantana Yahuafai (J)

Natural Products Research Section, Research Division, National Cancer Institute, Bangkok 10400, Thailand.

Pongpun Siripong (P)

Natural Products Research Section, Research Division, National Cancer Institute, Bangkok 10400, Thailand.

Somdej Kanokmedhakul (S)

Natural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address: somdej@kku.ac.th.

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Classifications MeSH