A Rare Presentation of Orbital Castleman's Disease.
Journal
Case reports in ophthalmological medicine
ISSN: 2090-6722
Titre abrégé: Case Rep Ophthalmol Med
Pays: United States
ID NLM: 101581018
Informations de publication
Date de publication:
2020
2020
Historique:
received:
18
09
2019
accepted:
09
12
2019
entrez:
28
1
2020
pubmed:
28
1
2020
medline:
28
1
2020
Statut:
epublish
Résumé
Castleman's disease (CD) is an uncommon group of atypical lymphoproliferative disorders. Extranodal involvement such as the orbit is extremely rare. We aim to report a case of a 62-year-old male who presented with left painless proptosis for the past three years. Examination revealed a firm, lobulated mass in the left superotemporal orbit, displacing the globe inferomedially. A well-defined extraconal orbital lesion encasing the left lateral rectus muscle with intraconal extension was seen on Magnetic Resonance Imaging (MRI) that led to the provisional diagnosis of left solitary encapsulated venous malformation. Excision of the mass via lateral orbitotomy was performed. However, on histopathology, the features were consistent with a mixed-cell variant of Castleman's disease. A detailed systemic workup was unremarkable. Proptosis resolved after surgery and no recurrence was noted in the three-year follow-up. To the best of our knowledge, this is the first case report of a mixed-cell variant of unicentric orbital CD without any systemic features. This case highlights the importance of including CD in the differential diagnosis of well-defined orbital lesions so as to enable its early detection and timely management.
Identifiants
pubmed: 31984145
doi: 10.1155/2020/1012759
pmc: PMC6964713
doi:
Types de publication
Case Reports
Langues
eng
Pagination
1012759Informations de copyright
Copyright © 2020 Ruchi Goel et al.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest regarding the publication of this paper.
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