Impact of donor lung quality on post-transplant recipient outcome in the Lung Allocation Score era in Eurotransplant - a historical prospective study.


Journal

Transplant international : official journal of the European Society for Organ Transplantation
ISSN: 1432-2277
Titre abrégé: Transpl Int
Pays: Switzerland
ID NLM: 8908516

Informations de publication

Date de publication:
05 2020
Historique:
received: 26 07 2019
revised: 02 09 2019
accepted: 20 01 2020
pubmed: 28 1 2020
medline: 25 6 2021
entrez: 28 1 2020
Statut: ppublish

Résumé

The aim of this study was to investigate whether there is an impact of donation rates on the quality of lungs used for transplantation and whether donor lung quality affects post-transplant outcome in the current Lung Allocation Score era. All consecutive adult LTx performed in Eurotransplant (ET) between January 2012 and December 2016 were included (N = 3053). Donors used for LTx in countries with high donation rate were younger (42% vs. 33% ≤45 years, P < 0.0001), were less often smokers (35% vs. 46%, P < 0.0001), had more often clear chest X-rays (82% vs. 72%, P < 0.0001), had better donor oxygenation ratios (20% vs. 26% with PaO

Identifiants

pubmed: 31984577
doi: 10.1111/tri.13582
pmc: PMC7216955
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

544-554

Informations de copyright

© 2020 Eurotransplant International Foundation. Transplant International published by John Wiley & Sons Ltd on behalf of Steunstichting ESOT.

Références

Transpl Int. 2011 Apr;24(4):393-400
pubmed: 21155901
Health Technol Assess. 2009 May;13(26):iii, ix-xi, 1-95
pubmed: 19422754
J Heart Lung Transplant. 2003 Nov;22(11):1183-200
pubmed: 14585380
Transplant Proc. 2012 Sep;44(7):1830-4
pubmed: 22974848
Am J Transplant. 2014 Jun;14(6):1318-27
pubmed: 24854023
Transpl Int. 2014 Nov;27(11):1183-91
pubmed: 25070600
Dig Dis Sci. 2019 May;64(5):1346-1355
pubmed: 30519849
Kidney Int. 2019 Jun;95(6):1453-1460
pubmed: 31010718
Ann Intern Med. 2010 Nov 16;153(10):641-9
pubmed: 21079219
J Heart Lung Transplant. 2017 Jul;36(7):744-753
pubmed: 28314503
Transplantation. 2014 Oct 27;98(8):903-8
pubmed: 24825527
J Heart Lung Transplant. 2015 Oct;34(10):1325-33
pubmed: 26186805
Transplantation. 2012 Dec 15;94(11):1167-71
pubmed: 23114533
Lancet Respir Med. 2018 May;6(5):357-367
pubmed: 29650408
Lancet Respir Med. 2019 Nov;7(11):975-984
pubmed: 31378427
Transpl Int. 2017 Oct;30(10):1002-1010
pubmed: 28556538
Curr Opin Organ Transplant. 2015 Oct;20(5):498-505
pubmed: 26262464
Ann Thorac Surg. 2007 Jan;83(1):257-63
pubmed: 17184674
Scand J Public Health. 2019 Apr 11;:1403494819833797
pubmed: 30973069
Am J Transplant. 2006;6(5 Pt 2):1212-27
pubmed: 16613597
Transplant Proc. 2013 May;45(4):1316-7
pubmed: 23726561
Proc Am Thorac Soc. 2009 Jan 15;6(1):28-38
pubmed: 19131528
Transpl Int. 2015 Feb;28(2):170-9
pubmed: 25266074

Auteurs

Jacqueline M Smits (JM)

Eurotransplant International Foundation, Leiden, The Netherlands.

Jens Gottlieb (J)

Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Biomedical Research in End-stage and Obstructive Disease (Breath), German Centre for Lung Research (DZL), Hannover, Germany.

Erik Verschuuren (E)

Department of Pulmonary Medicine and Tuberculosis, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Patrick Evrard (P)

Department of Intensive Care, Centre Hospitalier Universitaire Université Catholique de Louvain, Namur Godinne, Belgium.

Rogier Hoek (R)

Department of Pulmonary Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

Christiane Knoop (C)

Department of Respiratory Medicine, Hôpital Erasme, Brussels, Belgium.

György Lang (G)

Department of Thoracic Surgery, University Hospital, Vienna, Austria.

Johanna M Kwakkel-van Erp (JM)

Department of Respiratory Medicine, University Hospital Antwerp and University of Antwerp, Antwerp, Belgium.

Robin Vos (R)

Department of Respiratory Medicine, University Hospital Gasthuisberg, Leuven, Belgium.

Geert Verleden (G)

Department of Respiratory Medicine, University Hospital Gasthuisberg, Leuven, Belgium.

Benoit Rondelet (B)

Department of Thoracic Surgery, Centre Hospitalier Universitaire Université Catholique de Louvain, Namur Godinne, Belgium.

Daniel Hoefer (D)

Department of Thoracic and Cardiovascular Surgery, University Hospital Innsbruck, Innsbruck, Austria.

Frank Langer (F)

Department of Thoracic and Cardiovascular Surgery, University Hospital Saarland, Homburg, Germany.

Rene Schramm (R)

Department of Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine-Westphalia, Ruhr-University Bochum, Bad Oeyenhausen, Germany.

Konrad Hoetzenecker (K)

Department of Thoracic Surgery, University Hospital, Vienna, Austria.

Diana van Kessel (D)

Department of Respiratory Medicine, St Antonius Hospital, Nieuwegein, The Netherlands.

Bart Luijk (B)

Division of Heart and Lungs, Department of Respiratory Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.

Leonard Seghers (L)

Department of Pulmonary Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

Tobias Deuse (T)

Department of Thoracic and Cardiovascular Surgery, University Hospital Eppendorf, Hamburg, Germany.

Roland Buhl (R)

Department of Respiratory Medicine, University Hospital Mainz, Mainz, Germany.

Christian Witt (C)

Department of Respiratory Medicine, University Hospital Charité, Berlin, Germany.

Agita Strelniece (A)

Eurotransplant International Foundation, Leiden, The Netherlands.

Dave Green (D)

Eurotransplant International Foundation, Leiden, The Netherlands.

Erwin de Vries (E)

Eurotransplant International Foundation, Leiden, The Netherlands.

Guenter Laufer (G)

Department of Cardiac Surgery, University Hospital Vienna, Vienna, Austria.

Dirk Van Raemdonck (D)

Department of Thoracic Surgery, University Hospital Gasthuisberg, Leuven, Belgium.

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