Coronary Artery Disease and Type 2 Diabetes: A Proteomic Study.
Aged
Cohort Studies
Computed Tomography Angiography
Coronary Angiography
/ methods
Coronary Artery Disease
/ diagnosis
Diabetes Mellitus, Type 2
/ complications
Diabetic Angiopathies
/ diagnosis
Female
Humans
Male
Middle Aged
Prevalence
Proteome
/ analysis
Proteomics
/ methods
Risk Factors
Tomography, X-Ray Computed
/ methods
Journal
Diabetes care
ISSN: 1935-5548
Titre abrégé: Diabetes Care
Pays: United States
ID NLM: 7805975
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
received:
24
09
2019
accepted:
31
12
2019
pubmed:
29
1
2020
medline:
15
12
2020
entrez:
29
1
2020
Statut:
ppublish
Résumé
Coronary artery disease (CAD) is a major challenge in patients with type 2 diabetes (T2D). Coronary computed tomography angiography (CCTA) provides a detailed anatomic map of the coronary circulation. Proteomics are increasingly used to improve diagnostic and therapeutic algorithms. We hypothesized that the protein panel is differentially associated with T2D and CAD. In CAPIRE (Coronary Atherosclerosis in Outlier Subjects: Protective and Novel Individual Risk Factors Evaluation-a cohort of 528 individuals with no previous cardiovascular event undergoing CCTA), participants were grouped into CAD Though CAD We concluded that
Identifiants
pubmed: 31988066
pii: dc19-1902
doi: 10.2337/dc19-1902
doi:
Substances chimiques
Proteome
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
843-851Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2020 by the American Diabetes Association.