Association of Cirrhosis and Cardiomyopathy.
Cardiomyopathy
Cirrhosis
Pro-BNP
QT prolongation
Troponin-I
Journal
Euroasian journal of hepato-gastroenterology
ISSN: 2231-5047
Titre abrégé: Euroasian J Hepatogastroenterol
Pays: India
ID NLM: 101577625
Informations de publication
Date de publication:
Historique:
entrez:
29
1
2020
pubmed:
29
1
2020
medline:
29
1
2020
Statut:
ppublish
Résumé
We investigated association of pro-BNP, troponin-I, electrocardiography (ECG) and echocardiography (ECHO) during diagnosis and identification of cirrhotic cardiomyopathy in cirrhotic patients. Patients were divided into three groups as; compensated cirrhotic patients (group 1, n= 30), decompensated cirrhotic (group 2, n = 30) and control group (group 3, n = 30). ECHO, and ECG were performed, and troponin-I and levels of pro-BNP were analyzed. Average age of group 1 was 46.36 ± 16 years (range 19-86), 60% were female; group 2 was 57.03 ± 13.54 years (range 22-89), 56% female; and group 3 was 49.13 ± 0.95 years (range 18-80), 56% female. A significant increase in QTc was detected in compensated cirrhotic patients compared to the control group (p <0.05). Pro-BNP levels were significantly higher (p <0.05) in the compensated cirrhotic group compared to the control group. The levels of pro-BNP were also significantly higher in the decompensated cirrhotic group compared compensated cirrhosis group and control group (p <0.001). The increase of pro-BNP levels with severity of the disease in cirrhotic patients and the prolongation of QTc interval supports an association between these factors with cardiomyopathy. Sezgin B, Cindoglu C, et al. Association of Cirrhosis and Cardiomyopathy. Euroasian J Hepatogastroenterol 2019;9(1):23-26.
Identifiants
pubmed: 31988863
doi: 10.5005/jp-journals-10018-1291
pmc: PMC6969323
doi:
Types de publication
Journal Article
Langues
eng
Pagination
23-26Informations de copyright
Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.
Déclaration de conflit d'intérêts
Source of support: This research, supported Harran University Research Fund Project 12118 Conflict of interest: None
Références
J Hepatol. 2005 Jan;42(1):68-74
pubmed: 15629509
Arch Med Res. 2015 Apr;46(3):207-13
pubmed: 25843561
J Am Coll Cardiol. 1994 Jun;23(7):1554-6
pubmed: 8195513
Orphanet J Rare Dis. 2007 Mar 27;2:15
pubmed: 17389039
Gastroenterology. 2001 Nov;121(5):1209-18
pubmed: 11677214
Circulation. 1981 Oct;64(4):744-53
pubmed: 7273375
Eur J Cardiothorac Surg. 2008 Aug;34(2):307-12
pubmed: 18539042
Am J Gastroenterol. 1997 May;92(5):852-7
pubmed: 9149200
World J Hepatol. 2015 Nov 8;7(25):2571-7
pubmed: 26557949
Wien Klin Wochenschr. 2013 Apr;125(7-8):200-19
pubmed: 23579878
Scand J Gastroenterol. 2015 Jun;50(6):763-80
pubmed: 25881709
J Am Soc Echocardiogr. 2000 May;13(5):379-84
pubmed: 10804435
J Cardiol. 2016 Feb;67(2):125-30
pubmed: 26074443
J Hepatol. 2010 Jul;53(1):179-90
pubmed: 20462649
Clin Physiol Funct Imaging. 2017 Jul;37(4):347-356
pubmed: 26541640
Int J Clin Exp Med. 2015 Aug 15;8(8):13464-72
pubmed: 26550283
Handb Exp Pharmacol. 2009;(191):341-66
pubmed: 19089336
Lancet. 2003 Jul 26;362(9380):316-22
pubmed: 12892964
Eur J Intern Med. 2015 Dec;26(10):830-4
pubmed: 26525531