How much energy do we need to ablate 1 mm


Journal

World journal of urology
ISSN: 1433-8726
Titre abrégé: World J Urol
Pays: Germany
ID NLM: 8307716

Informations de publication

Date de publication:
Nov 2020
Historique:
received: 26 10 2019
accepted: 09 01 2020
pubmed: 29 1 2020
medline: 22 6 2021
entrez: 29 1 2020
Statut: ppublish

Résumé

Holmium:yttrium-aluminium-garnet (Ho:YAG) is currently the gold standard for lithotripsy for the treatment of all known urinary stone types. Stone composition and volume are major determinants of the lithotripsy. This in vitro study evaluated the required energy to ablate 1 mm 272 µm core-diameter laser fibers (Boston Scientific All settings considered, ablation volumes per pulse (AVP) for COM were significantly lower than those for UA and Cys (p = 0.002 and p = 0.03, respectively), whereas AVP for Cys was significantly lower than those for UA (p = 0.03). The mean REs at 0.6 J pulse energy (PE) for COM, Cys and UA were 34, 8.5 and 3.2 J, respectively The mean REs at 1 J PE for COM, Cys and UA were 14.7, 6.4 and 2 J, respectively. At 0.6 J PE, RE for COM was more than tenfold and fivefold higher than those for UA and Cys, respectively. This in vitro study shows for the first time a volumetric evaluation of Ho:YAG efficiency by the ablation volume per pulse on human stone samples, according to various pulse energies. The REs for COM, UA and Cys should be considered in clinical practice.

Identifiants

pubmed: 31989208
doi: 10.1007/s00345-020-03091-5
pii: 10.1007/s00345-020-03091-5
doi:

Substances chimiques

Calcium Oxalate 2612HC57YE
Uric Acid 268B43MJ25
Cystine 48TCX9A1VT

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2945-2953

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Auteurs

Frédéric Panthier (F)

GRC No 20, Groupe de Recherche Clinique Sur La Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France.
Service D'Urologie, Assistance-Publique Hôpitaux de Paris, Hôpital Tenon, Sorbonne Université, 4 rue de la Chine, 75020, Paris, France.
PIMM, UMR 8006 CNRS-Arts Et Métiers ParisTech, 151 bd de l'Hôpital, 75013, Paris, France.

Eugenio Ventimiglia (E)

GRC No 20, Groupe de Recherche Clinique Sur La Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France.
Service D'Urologie, Assistance-Publique Hôpitaux de Paris, Hôpital Tenon, Sorbonne Université, 4 rue de la Chine, 75020, Paris, France.
Division of Experimental Oncology/Unit of Urology, URI-Urological Research Institute, IRCCS Ospedale San Raffaele, 20132, Milan, Italy.

Laurent Berthe (L)

PIMM, UMR 8006 CNRS-Arts Et Métiers ParisTech, 151 bd de l'Hôpital, 75013, Paris, France.

Catherine Chaussain (C)

Plateforme D'imagerie du Vivant, EA 2496 Orofacial Pathologies, Imagery and Biotherapies, Dental School Faculty, University Paris Descartes and Life Imaging Plateform (PIV), Montrouge, France.

Michel Daudon (M)

GRC No 20, Groupe de Recherche Clinique Sur La Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France.
Service Des Explorations Fonctionnelles, Hopital TENON, 4 rue de la Chine, Paris, France.

Steeve Doizi (S)

GRC No 20, Groupe de Recherche Clinique Sur La Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France.
Service D'Urologie, Assistance-Publique Hôpitaux de Paris, Hôpital Tenon, Sorbonne Université, 4 rue de la Chine, 75020, Paris, France.

Olivier Traxer (O)

GRC No 20, Groupe de Recherche Clinique Sur La Lithiase Urinaire, Hôpital Tenon, Sorbonne Université, 75020, Paris, France. olivier.traxer@aphp.fr.
Service D'Urologie, Assistance-Publique Hôpitaux de Paris, Hôpital Tenon, Sorbonne Université, 4 rue de la Chine, 75020, Paris, France. olivier.traxer@aphp.fr.

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