Sultiame pharmacokinetic profile in plasma and erythrocytes after single oral doses: A pilot study in healthy volunteers.
clearance
healthy volunteers
pharmacokinetic
sultiame
volume of distribution
Journal
Pharmacology research & perspectives
ISSN: 2052-1707
Titre abrégé: Pharmacol Res Perspect
Pays: United States
ID NLM: 101626369
Informations de publication
Date de publication:
02 2020
02 2020
Historique:
received:
09
12
2019
accepted:
13
12
2019
entrez:
29
1
2020
pubmed:
29
1
2020
medline:
24
10
2020
Statut:
ppublish
Résumé
A pilot study was conducted aiming at specifying sultiame's pharmacokinetic profile, completed by in vitro assays evaluating the intraerythrocytic transfer of sultiame and by a pharmacokinetic model assessing its distribution. Single oral doses of sultiame (Ospolot
Identifiants
pubmed: 31990440
doi: 10.1002/prp2.558
pmc: PMC6986439
doi:
Substances chimiques
Thiazines
0
sulthiame
I00Q766CZ2
Types de publication
Clinical Trial
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e00558Informations de copyright
© 2020 The Authors. Pharmacology Research & Perspectives published by John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics.
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