Comparative Study of the Effect of 5,6-Dihydroergosterol and 3-
3-epi-5,6-dihydroergosterol glycoside
CCL17/TARC
CCL22/MDC
anti-inflammation
chronic dermatitis treatment
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
25 Jan 2020
25 Jan 2020
Historique:
received:
09
01
2020
revised:
21
01
2020
accepted:
22
01
2020
entrez:
30
1
2020
pubmed:
30
1
2020
medline:
12
11
2020
Statut:
epublish
Résumé
5,6-Dihydroergosterol-glucose is an organic synthetic derivative of spinasterol-glucose, which has potent anti-inflammatory activity. We previously synthesized alpha and beta anomers of DHE-glycosides and compared their inhibitory activity on CCL17 and CCL22 mRNA expression induced by TNF-α/IFN-γ in activated HaCaTs. Recently, we synthesized a new type of DHE-glycosides, 3-
Identifiants
pubmed: 31991764
pii: molecules25030522
doi: 10.3390/molecules25030522
pmc: PMC7036979
pii:
doi:
Substances chimiques
Chemokines
0
Cytokines
0
Ergosterol
Z30RAY509F
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Gyeonggi province
ID : GRRC-KyungHee-2018(B01)
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest.
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