The coupling apparatus of the sperm head and tail†.
acephalic spermatozoa syndrome
evolution
head–tail coupling apparatus
sperm competition
Journal
Biology of reproduction
ISSN: 1529-7268
Titre abrégé: Biol Reprod
Pays: United States
ID NLM: 0207224
Informations de publication
Date de publication:
24 04 2020
24 04 2020
Historique:
received:
30
04
2019
revised:
05
08
2019
accepted:
26
01
2020
pubmed:
30
1
2020
medline:
20
8
2021
entrez:
30
1
2020
Statut:
ppublish
Résumé
A strong sperm head-tail coupling apparatus (HTCA) is needed to ensure the integrity of spermatozoa during their fierce competition to fertilize the egg. A lot of HTCA-specific components have evolved to strengthen the attachment of the tail to the implantation fossa at the sperm head. Defects in HTCA formation lead to acephalic spermatozoa syndrome and pathologies of some male infertility. Recent studies have provided insights into the pathogenic molecular mechanisms of acephalic spermatozoa syndrome. Here, we summarize the proteins involved in sperm neck development and focus on their roles in the formation of HTCA. In addition, we discuss the fine structures of the sperm neck in different species from an evolutionary view, highlighting the potential conservative mechanism of HTCA formation.
Identifiants
pubmed: 31995163
pii: 5717438
doi: 10.1093/biolre/ioaa016
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
988-998Informations de copyright
© The Author(s) 2020. Published by Oxford University Press on behalf of Society for the Study of Reproduction. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.