Smoking history is negatively associated with allergen specific immunotherapy efficacy: a retrospective analysis.
grass pollen
house dust mite
rhinitis
tobacco
Journal
Postepy dermatologii i alergologii
ISSN: 1642-395X
Titre abrégé: Postepy Dermatol Alergol
Pays: Poland
ID NLM: 101168357
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
05
03
2018
accepted:
11
07
2018
entrez:
31
1
2020
pubmed:
31
1
2020
medline:
31
1
2020
Statut:
ppublish
Résumé
Allergen specific immunotherapy (AIT) is the only treatment modifying the course of the disease in patients allergic to airborne allergens. It has been proven to be effective in allergic populations, however individual patients vary in terms of response to the therapy. To assess the factors that might affect the efficacy of AIT. Patients treated with AIT for grass pollen or house dust mites were included. The efficacy of AIT was assessed with the use of Allergy Control Score (ACS), performed before and at least 1 year after AIT. The following variables were assessed as potential risk factors for a worse response to AIT: age, gender, type of allergy, type of allergen, type of vaccine, type of AIT and smoking history. The study group consisted of 145 subjects.AIT was effective in the entire group; the mean ACS results decreased from 21.14 to 14.41 points ( Smoking history may affect AIT outcomes.
Identifiants
pubmed: 31997993
doi: 10.5114/ada.2018.80654
pii: 80654
pmc: PMC6986293
doi:
Types de publication
Journal Article
Langues
eng
Pagination
673-676Informations de copyright
Copyright © 2019 Termedia.
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