Neonatal Acute Liver Failure.

Humans Infant, Newborn Liver Failure, Acute / congenital Neonatal Screening Prognosis Rare Diseases / congenital
Gestational alloimmune liver disease Liver failure Liver transplant Neonatal

Journal

Clinics in perinatology
ISSN: 1557-9840
Titre abrégé: Clin Perinatol
Pays: United States
ID NLM: 7501306

Informations de publication

Date de publication:
03 2020
Historique:
entrez: 1 2 2020
pubmed: 1 2 2020
medline: 18 8 2021
Statut: ppublish

Résumé

Neonatal acute liver failure (NALF) is a rare disease with a few known primary causes: gestational alloimmune liver disease (GALD), viral infections, metabolic diseases, and ischemic injury. Many cases still do not have a known cause. Laboratory evaluation may suggest a diagnosis. Most of the known causes have disease-specific treatments that improve outcomes. Survival is improving with better knowledge about and treatment options for GALD; however, overall mortality for NALF is still 24%. Liver transplant remains an important option for neonates with an indeterminate cause of NALF and those who do not respond to established treatments.

Identifiants

DOI: 10.1016/j.clp.2019.10.006 PMID: 32000927
pubmed: 32000927
pii: S0095-5108(19)30126-5
doi: 10.1016/j.clp.2019.10.006
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

25-39

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors have nothing to disclose.

Auteurs

Catherine Larson-Nath (C)

Pediatric Gastroenterology, Hepatology & Nutrition, University of Minnesota, 2450 Riverside Avenue, Minneapolis, MN 55454, USA.

Bernadette E Vitola (BE)

Pediatric Gastroenterology, Hepatology & Nutrition, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA. Electronic address: bvitola@mcw.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Neonatal Acute Liver Failure.
questionsmedicales.fr › Personnes › Tranches d'âge › Nourrisson › Nouveau-né › Neonatal Acute Liver Failure.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Insuffisance hépatique › Défaillance hépatique › Défaillance hépatique aigüe › Neonatal Acute Liver Failure.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Dépistage de masse › Dépistage néonatal › Neonatal Acute Liver Failure.
questionsmedicales.fr › Diagnostic › Pronostic › Neonatal Acute Liver Failure.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladies rares › Neonatal Acute Liver Failure.