Time course determination of the effects of rapid and gradual cooling after acute hyperthermia on body temperature and intestinal integrity in pigs.
Hyperthermia
Intestinal permeability
Pigs
Rapid cooling
gradual cooling
Journal
Journal of thermal biology
ISSN: 0306-4565
Titre abrégé: J Therm Biol
Pays: England
ID NLM: 7600115
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
received:
23
10
2019
revised:
06
12
2019
accepted:
07
12
2019
entrez:
1
2
2020
pubmed:
1
2
2020
medline:
9
10
2020
Statut:
ppublish
Résumé
Rapid cooling after acute hyperthermia may cause a sustained increase in body temperature and exacerbate intestinal damage in pigs. Therefore, the study objective was to evaluate the temporal effects of rapid and gradual cooling on body temperature response and intestinal integrity after acute hyperthermia in pigs. In three repetitions, 54 pigs [83.3 ± 6.7 kg initial body weight (BW)], balanced by sex were exposed to thermoneutral conditions for 6 h (TN; n = 6 pigs/repetition; 21.1 ± 2.0°C), or heat stress conditions (HS; 39.3 ± 1.6°C) for 3 h, followed by a 3 h recovery period of gradual cooling [HSGC; n = 6 pigs/repetition; gradual decrease from HS to TN conditions] or rapid cooling [HSRC; n = 6 pigs/repetition; rapid TN exposure and cold water (4.0°C) dousing every 30 min for 1.5 h]. Feed was withheld throughout the entire 6 h period, but water was provided ad libitum. Gastrointestinal (T
Identifiants
pubmed: 32001015
pii: S0306-4565(19)30593-5
doi: 10.1016/j.jtherbio.2019.102481
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
102481Informations de copyright
Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
Declaration of competing interest No conflict of interest, financial, or otherwise are declared by the author(s).