Severe metallosis-related osteolysis as a cause of failure after total knee replacement.

Arthroplasty Metal on metal Metallosis Polyethylene wear Revision total knee replacement

Journal

Journal of clinical orthopaedics and trauma
ISSN: 0976-5662
Titre abrégé: J Clin Orthop Trauma
Pays: India
ID NLM: 101559469

Informations de publication

Date de publication:
Historique:
received: 12 01 2019
revised: 15 04 2019
accepted: 17 04 2019
entrez: 1 2 2020
pubmed: 1 2 2020
medline: 1 2 2020
Statut: ppublish

Résumé

Metallosis is a syndrome of metal-induced synovitis caused by friction between two metal surfaces. In contrast to the hip joint after resurfacing arthroplasty or metal-on-metal (MoM) total hip replacement, metallosis of the knee is extremely rare. We describe 4 patients who underwent revision total knee replacement because of disabling pain and implant loosening after a mean time of 21 (range: 13-30) years of knee replacement surgery. They were all females with a mean age of 79 (range: 75-82) years. Septic loosening was excluded through microbiological examination and synovial fluid analysis. Direct metal-on-metal contact at the tibiofemoral interface was confirmed intraoperatively in all cases. All knees showed severe metallosis with advanced osteolysis and pseudotumor formation. In one knee there was a complete fracture of the tibial tray. All patients had a one-stage revision surgery with implant removal, profound synovectomy and implantation of a constrained modular revision knee system. Long modular stems with offset adapters, wedges and/or blocks were used in all cases. Metallosis-associated osteolysis should be suspected in cases with radiologically evident polyethylene wear after knee replacement. Recognizing that revision arthroplasty is very technically demanding in such cases, surgeons should have a back-up with modular revision components and a ready access to reconstructive options at this revision setting.

Sections du résumé

BACKGROUND BACKGROUND
Metallosis is a syndrome of metal-induced synovitis caused by friction between two metal surfaces. In contrast to the hip joint after resurfacing arthroplasty or metal-on-metal (MoM) total hip replacement, metallosis of the knee is extremely rare.
MATERIALS METHODS
We describe 4 patients who underwent revision total knee replacement because of disabling pain and implant loosening after a mean time of 21 (range: 13-30) years of knee replacement surgery. They were all females with a mean age of 79 (range: 75-82) years. Septic loosening was excluded through microbiological examination and synovial fluid analysis.
RESULTS RESULTS
Direct metal-on-metal contact at the tibiofemoral interface was confirmed intraoperatively in all cases. All knees showed severe metallosis with advanced osteolysis and pseudotumor formation. In one knee there was a complete fracture of the tibial tray. All patients had a one-stage revision surgery with implant removal, profound synovectomy and implantation of a constrained modular revision knee system. Long modular stems with offset adapters, wedges and/or blocks were used in all cases.
CONCLUSION CONCLUSIONS
Metallosis-associated osteolysis should be suspected in cases with radiologically evident polyethylene wear after knee replacement. Recognizing that revision arthroplasty is very technically demanding in such cases, surgeons should have a back-up with modular revision components and a ready access to reconstructive options at this revision setting.

Identifiants

pubmed: 32002007
doi: 10.1016/j.jcot.2019.04.010
pii: S0976-5662(19)30050-5
pmc: PMC6985032
doi:

Types de publication

Journal Article

Langues

eng

Pagination

165-170

Informations de copyright

© 2019 Delhi Orthopedic Association. All rights reserved.

Références

Am J Orthop (Belle Mead NJ). 1997 Sep;26(9):598-600
pubmed: 9316720
J Arthroplasty. 2005 Aug;20(5):568-73
pubmed: 16309990
Mod Rheumatol. 2007;17(6):507-10
pubmed: 18084705
BMJ Case Rep. 2014 Mar 18;2014:null
pubmed: 24642179
J Bone Joint Surg Am. 2006 Jun;88(6):1183-91
pubmed: 16757749
Int J Immunopathol Pharmacol. 2011 Jul-Sep;24(3):711-9
pubmed: 21978703
J Arthroplasty. 2007 Sep;22(6):909-15
pubmed: 17826284
J Bone Joint Surg Am. 1991 Aug;73(7):1002-7
pubmed: 1874762
Skeletal Radiol. 2008 Jan;37(1):59-62
pubmed: 17876581
Acta Chir Orthop Traumatol Cech. 2003;70(1):47-50
pubmed: 12764951
J Med Case Rep. 2009 Nov 29;3:9304
pubmed: 20062793
J Bone Joint Surg Br. 2009 Aug;91(8):1025-30
pubmed: 19651828
J Hand Surg Am. 2006 Dec;31(10):1615-8
pubmed: 17145381
J Arthroplasty. 1998 Jan;13(1):116-9
pubmed: 9493550
Int Orthop. 2019 Jan;43(1):85-96
pubmed: 30269183
Int J Surg Case Rep. 2017;30:9-12
pubmed: 27898357
Acta Orthop. 2009 Dec;80(6):653-9
pubmed: 19995315
J Bone Joint Surg Br. 2011 Feb;93(2):205-9
pubmed: 21282760
J Biomed Mater Res A. 2007 Jun 15;81(4):1005-10
pubmed: 17265437
J Radiol Case Rep. 2010;4(9):7-17
pubmed: 22470753
Acta Orthop Belg. 2008 Dec;74(6):753-60
pubmed: 19205321
Knee Surg Sports Traumatol Arthrosc. 2007 Apr;15(4):361-4
pubmed: 17028866
Orthopedics. 1997 May;20(5):466-70
pubmed: 9172254
Pathol Eur. 1970;5(3):307-14
pubmed: 5477026
J Orthop Case Rep. 2015 Apr-Jun;5(2):62-5
pubmed: 27299048
J Orthop Case Rep. 2014 Jan-Mar;4(1):21-3
pubmed: 27298939
J Arthroplasty. 1996 Dec;11(8):923-30
pubmed: 8986570
AJR Am J Roentgenol. 1998 Jun;170(6):1556
pubmed: 9609173
J Bone Joint Surg Br. 2008 Apr;90(4):502-5
pubmed: 18378928

Auteurs

Khaled Hamed Salem (KH)

Department of Orthopaedic Surgery, Faculty of Medicine, Cairo University, Egypt.
Department of Orthopaedic Surgery, Brüderkrankenhaus St. Josef Paderborn, Germany.
Department of Orthopaedic Surgery, RWTH Aachen University, Germany.

Norbert Lindner (N)

Department of Orthopaedic Surgery, Brüderkrankenhaus St. Josef Paderborn, Germany.

Markus Tingart (M)

Department of Orthopaedic Surgery, RWTH Aachen University, Germany.

Alyaa Diaa Elmoghazy (AD)

Department of Orthopaedic Surgery, Brüderkrankenhaus St. Josef Paderborn, Germany.
Department of Orthopaedic Surgery, RWTH Aachen University, Germany.

Classifications MeSH