Inflammatory Bowel Disease in Japan-Is It Similar to or Different from Westerns?

Crohn's disease inflammatory bowel disease ulcerative colitis

Journal

Journal of the anus, rectum and colon
ISSN: 2432-3853
Titre abrégé: J Anus Rectum Colon
Pays: Japan
ID NLM: 101718055

Informations de publication

Date de publication:
2020
Historique:
received: 18 01 2019
accepted: 08 07 2019
entrez: 1 2 2020
pubmed: 1 2 2020
medline: 1 2 2020
Statut: epublish

Résumé

Ulcerative colitis and Crohn's disease, the most common types of inflammatory bowel disease, are idiopathic, intractable disease characterized by chronic inflammation in the intestine. In recent years, studies elucidating the clinical characteristics of these diseases and basic researches have suggested that the diseases are induced by the immunological abnormalities through the involvement of environmental factors with their predisposition. In Japan, significant progress of basic and epidemiological researches has been developed for these diseases and the clinical guidelines have been established. However, no fundamental treatment for these diseases has been established yet. The current number of patients in Japan continues to increase, with at least 180,000 patients suffering from ulcerative colitis and 40,000 suffering from Crohn's disease. Thus, further studies are required to understand these diseases and improve medical treatments.

Identifiants

pubmed: 32002471
doi: 10.23922/jarc.2019-003
pmc: PMC6989123
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1-13

Informations de copyright

Copyright © 2020 by The Japan Society of Coloproctology.

Déclaration de conflit d'intérêts

Conflicts of Interest Toshifumi Hibi received lecture fees from Mitsubishi-Tanabe Pharma, Kyorin Pharmaceutical, Abbvie GK, Janssen, Mochida Pharmaceutical, JIMRO, Takeda Pharmaceutical, Gilead Sciences, Kissei Pharmaceutical, Zeria Pharmaceutical, Ferring Pharmaceutical and Nippon Kayaku, advisory/consultancy fees from Mitsubishi-Tanabe Pharma, Takeda Pharmaceutical, EA Pharma, Janssen, Eli Lilly, Pfizer and Zeria Pharmaceutical and research grant from Abbvie GK, JIMRO and Zeria Pharmaceutical.

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Auteurs

Shinji Okabayashi (S)

Center for Advanced IBD Research and Treatment, Kitasato Institute Hospital, Kitasato University, Tokyo, Japan.

Taku Kobayashi (T)

Center for Advanced IBD Research and Treatment, Kitasato Institute Hospital, Kitasato University, Tokyo, Japan.

Toshifumi Hibi (T)

Center for Advanced IBD Research and Treatment, Kitasato Institute Hospital, Kitasato University, Tokyo, Japan.

Classifications MeSH