En-bloc resection of bladder tumors for pathological staging: the value of lateral margins analysis.
Journal
Minerva urologica e nefrologica = The Italian journal of urology and nephrology
ISSN: 1827-1758
Titre abrégé: Minerva Urol Nefrol
Pays: Italy
ID NLM: 8503649
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
pubmed:
1
2
2020
medline:
23
3
2021
entrez:
1
2
2020
Statut:
ppublish
Résumé
In endoscopic resection of colorectal tumors, the pathological assessment of the lateral margins is a strong predictor of tumor recurrence after resection. The aim of the current study is to evaluate the value of the peritumoral margins assessment in ERBT on tumor recurrence. We retrospectively analyzed the data of 50 consecutive patients with NMIBC and treated by ERBT between January and December 2017. The lateral margins showed dysplasia in 16 patients and malignancy in three patients. Local recurrence occurred in 14 (28%) patients. It was noted that 57% of patients with recurrence showed some degree of dysplasia or malignancy in the lateral margin; however, on multivariate logistic regression lateral margins lesions were not significantly associated with recurrence (OR 2.175, 95% CI: 0.430-10.996, P=0.35). ERBT may improve the pathological report of bladder tumor. There was a trend toward increased rate of recurrence in patients with dysplasia or malignancy in their lateral margins; however, this was not statistically significant on multivariate analysis. Further studies with larger sample sizes are required to assess the value of lateral margin analysis.
Sections du résumé
BACKGROUND
BACKGROUND
In endoscopic resection of colorectal tumors, the pathological assessment of the lateral margins is a strong predictor of tumor recurrence after resection. The aim of the current study is to evaluate the value of the peritumoral margins assessment in ERBT on tumor recurrence.
METHODS
METHODS
We retrospectively analyzed the data of 50 consecutive patients with NMIBC and treated by ERBT between January and December 2017.
RESULTS
RESULTS
The lateral margins showed dysplasia in 16 patients and malignancy in three patients. Local recurrence occurred in 14 (28%) patients. It was noted that 57% of patients with recurrence showed some degree of dysplasia or malignancy in the lateral margin; however, on multivariate logistic regression lateral margins lesions were not significantly associated with recurrence (OR 2.175, 95% CI: 0.430-10.996, P=0.35).
CONCLUSIONS
CONCLUSIONS
ERBT may improve the pathological report of bladder tumor. There was a trend toward increased rate of recurrence in patients with dysplasia or malignancy in their lateral margins; however, this was not statistically significant on multivariate analysis. Further studies with larger sample sizes are required to assess the value of lateral margin analysis.
Identifiants
pubmed: 32003203
pii: S0393-2249.20.03551-1
doi: 10.23736/S0393-2249.20.03551-1
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM