TWO-YEAR FOLLOW-UP OF A RETINAL ASTROCYTIC HAMARTOMA IMAGED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.
Journal
Retinal cases & brief reports
ISSN: 1937-1578
Titre abrégé: Retin Cases Brief Rep
Pays: United States
ID NLM: 101298744
Informations de publication
Date de publication:
01 May 2022
01 May 2022
Historique:
pubmed:
1
2
2020
medline:
29
4
2022
entrez:
1
2
2020
Statut:
ppublish
Résumé
To report a case of retinal astrocytic hamartoma imaged by optical coherence tomography angiography (OCTA), followed for 2 years. Observational case report. A 25-year-old woman was referred for an incidental retinal lesion in the left eye (LE). At baseline, the best-corrected visual acuity in the LE was 20/32, and fundus examination showed the presence of a round, pigmented lesion in juxtafoveal region, corresponding, on spectral domain OCT, to a hyperreflective lesion within nerve fiber layer. Optical coherence tomography angiography revealed the presence of a high-flow lesion in the superficial capillary plexus segmentation. The patient was followed up for 2 years: best-corrected visual acuity remained stable and multimodal imaging, including OCTA, confirmed the benign and stable nature of the lesion. At baseline, the total lesion area on OCTA (superficial capillary plexus) was 0.181 mm2, whereas vascular density was 52.080%; the total area was 0.204 mm2, and vascular density was 53.740% at 2-year follow-up. Optical coherence tomography angiography is helpful not only for the diagnosis and follow-up of such rare tumors, but also it gives insights as to how these tumors develop and how they affect surrounding structures.
Identifiants
pubmed: 32004181
pii: 01271216-202205000-00020
doi: 10.1097/ICB.0000000000000975
doi:
Types de publication
Case Reports
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
338-343Références
Destro M, D'Amico DJ, Gragoudas ES, et al. Retinal manifestations of neurofibromatosis Diagnosis and management. Arch Ophthalmol 1991;109:662–666.
Gass JDM. An unusual hamartoma of the pigment epithelium and retina simulating choroidal melanoma and retinoblastoma. Trans Am Ophthalmol 1973;71:171–185.
Shields JA, Shields CL. Glial tumors of the retina. The 2009 king khaled memorial lecture. Saudi J Ophthalmol 2009;23:197–201.
Kiratli H, Bilgiç S. Spontaneous regression of retinal astrocytic hamartoma in a patient with tuberous sclerosis. Am J Ophthalmol 2002;133:715–716.
Serafino M, Pichi F, Giuliari GP, et al. Retinal astrocytic hamartoma: spectral-domain optical coherence tomography classification and correlation with tuberous sclerosis complex. Retina 2016;36:1199–1208.
Yung M, Iafe N, Sarraf D. Optical coherence tomography angiography of a retinal astrocytic hamartoma. Can J Ophthalmol 2016;51:e62–4.
Goel N, Pangtey B, Bhushan G, et al. Spectral-domain optical coherence tomography of astrocytic hamartomas in tuberous sclerosis. Int Ophthalmol 2012;32:491–493.
Shields JA, Bianciotto CG, Kivela T, Shields CL. Presumed solitary circumscribed retinal astrocytic proliferation: the 2010 Jonathan W. Wirtschafter Lecture. Arch Ophthalmol 2011;129:1189–1194.
Shelton JB, Digre KB, Gilman J, et al. Characteristics of myelinated retinal nerve fiber layer in ophthalmic imaging: findings on autofluorescence, fluorescein angiographic, infrared, optical coherence tomographic, and red-free images. JAMA Ophthalmol 2013;131:107–109.
Shields CL, Benevides R, Materin MA, Shields JA. Optical coherence tomography of retinal astrocytic hamartoma in 15 cases. Am Acad Ophthalmol 2006;113:1553–1557.
Goldberg RA, Raja KM. Presumed solitary circumscribed retinal astrocytic proliferation in the fovea with OCT angiography: a misnomer. Ophthalmic Surg Lasers Imaging Retina 2018;49:212–214.