Evaluating the TARGET and EAT-ICU trials: how important are accurate caloric goals? Point-counterpoint: the pro position.


Journal

Current opinion in clinical nutrition and metabolic care
ISSN: 1473-6519
Titre abrégé: Curr Opin Clin Nutr Metab Care
Pays: England
ID NLM: 9804399

Informations de publication

Date de publication:
03 2020
Historique:
pubmed: 1 2 2020
medline: 11 6 2021
entrez: 1 2 2020
Statut: ppublish

Résumé

Controversies about the adequate amount of energy to deliver to critically ill patients are still going on, trying to find if hypocaloric or normocaloric regimen is beneficial in this population. Our purpose is to review recent publications using or not indirect calorimetry. Numerous studies have compared hypocaloric to normocaloric regimen using predictive equations. However, these equations have been demonstrated to be inaccurate in most of the cases. Some recent PRCT using indirect calorimetry are finding some advantages to isocalorie regimens, but others not. Timing of the nutrition respecting or not the early substrate endogenous production, use of an adequate amount of protein, respect of the daily variability of needs may explain the divergent results observed. Indirect calorimetry should be used to define the energy expenditure of the patient and to determine its requirements. More studies comparing isocalorie to hypocalorie regimens with fixed protein intake are necessary to confirm the observational and some of the PRCT-positive studies.

Identifiants

pubmed: 32004237
doi: 10.1097/MCO.0000000000000638
pii: 00075197-202003000-00007
doi:

Substances chimiques

Dietary Proteins 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

91-95

Références

Singer P, Blaser AR, Berger MM, et al. ESPEN guideline on clinical nutrition in the intensive care unit. Clin Nutr 2019; 38:48–79.
McClave SA, Taylor BE, Martindale RG, et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). J Parenteral Enteral Nutr 2016; 40:159–211.
Singer P, Anbar R, Cohen J, et al. The tight calorie control study (TICACOS): a prospective, randomized, controlled pilot study of nutritional support in critically ill patients. Intensive Care Med 2011; 37:601–609.
Heidegger CP, Berger MM, Graf S, et al. Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: a randomised controlled clinical trial. Lancet 2013; 381:385–393.
Perman MI, Ciapponi A, Franco JVA, et al. Prescribed hypocaloric nutrition support for critically-ill adults. Cochrane Database Syst Re 2018; 6: CD007867.
Silva CFA, de Vasconcelos SG, da Silva TA, Silva FM. Permissive or trophic enteral nutrition and full enteral nutrition had similar effects on clinical outcomes in intensive care: a systematic review of randomized clinical trials. Nutr Clin Pract 2018; 33:388–396.
Phan KA, Dux CM, Osland EJ, Reade MC. Effect of hypocaloric normoprotein or trophic feeding versus target full enteral feeding on patient outcomes in critically ill adults: a systematic review. Anaesth Intensive Care 2017; 45:663–675.
Wischmeyer PE, Hasselmann M, Kummerlen C, et al. A randomized trial of supplemental parenteral nutrition in underweight and overweight critically ill patients: the TOP-UP pilot trial. Crit Care 2017; 21:142.
Allingstrup MJ, Kondrup J, Wiis J, et al. Early goal-directed nutrition versus standard of care in adult intensive care patients: the single-centre, randomised, outcome assessor-blinded EAT-ICU trial. Intensive Care Med 2017; 43:1637–1647.
Chapman M, Peake SL, Bellomo R, et al. TARGET Investigators, for the ANZICS Clinical Trials Group. Energy-dense versus routine enteral nutrition in the critically ill. N Engl J Med 2018; 379:1823–1834.
Jung YT, Park JY, Jeon J, et al. Association of inadequate caloric supplementation with 30-day mortality in critically ill postoperative patients with high modified NUTRIC score. Nutrients 2018; 10: pii: E1589.
pii: e1589
Elke G, van Zanten AR, Lemieux M, et al. Enteral versus parenteral nutrition in critically ill patients: an updated systematic revew and meta-analysis of randomized controlled trials. Crit Care 2016; 20:117.
Villet S, Chiolero RL, Bollmann MD, et al. Negative impact of hypocaloric feeding and energy balance on clinical outcome in ICU patients. Clin Nutr 2005; 24:502-509.
Zusman O, Theilla M, Cohen J, et al. Resting energy expenditure, calorie and protein consumption in critically ill patients: a retrospective cohort study. Crit Care 2016; 20:367.
Tatucu-Babet OA, Ridley EJ, Tierney AC. Prevalence of underprescription or overprescription of energy needs in critically ill mechanically ventilated adults as determined by indirect calorimetry: a systematic literature review. JPEN J Parenter Enteral Nutr 2016; 40:212–225.
Petros S, Horbach M, Seidel F, Weidhase L. Hypocaloric vs normocaloric nutrition in critically ill patients: a prospective randomized pilot trial. JPEN J Parenter Enteral Nutr 2016; 40:242–249.
Theilla M, Kagan I, Rattanachaiwong S, Singer P. Is there an ebb phase (early hypometabolic period) after multiple trauma? Clin Nutr 2018; 37:S2.
Reitam Balser A, Berger MM. Early versus late feeding in the ICU. Nutrients 2019; 9:1278.
Oshima T, Berger MM, Waele ED, et al. Indirect calorimetry in nutritional therapy. A position paper by the ICALIC study group. Clinical Nutrition 2017; 36:651–662.
Singer P, Singer J. Clinical guide for the use of metabolic carts: indirect calorimetry—no longer the orphan of energy estimation. Nutr Clin Pract 2016; 31:30–38.
Oshima T, Deutz NE, Doig G, et al. Protein-energy nutrition in the ICU is the power couple: a hypothesis forming analysis. Clin Nutr 2016; 35:968–974.
Weijs PJM, Mogensen KM, Rawn JD, Christopher KB. Protein intake, nutritional status and outcomes in ICU survivors: a single center cohort study. J Clin Med 2019; 8: pii: E43.
pii: e43

Auteurs

Pierre Singer (P)

Department of General Intensive Care, Rabin Medical Center, Petah Tikva and Sackler School of Medicine, Tel Aviv University, Israel.

Claude Pichard (C)

Nutrition Unit, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, Geneva, Switzerland.

Sornwichate Rattanachaiwong (S)

Division of Clinical Nutrition, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

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