Chronic bursitis and tenosynovitis revealing Whipple's disease.


Journal

Joint bone spine
ISSN: 1778-7254
Titre abrégé: Joint Bone Spine
Pays: France
ID NLM: 100938016

Informations de publication

Date de publication:
Oct 2020
Historique:
received: 04 12 2019
accepted: 23 01 2020
pubmed: 3 2 2020
medline: 29 6 2021
entrez: 3 2 2020
Statut: ppublish

Résumé

Joint complaints, most commonly intermittent arthritis, are the initial manifestation in about three-fourths of Whipple's disease cases. We herein report on two cases wherein Whipple's disease manifested itself as chronic bursitis and tenosynovitis at several sites. A 42 year-old man had bilateral olecranon bursitis, a right patellar bursitis and an extensor tenosynovitis on the left wrist and a 54 year-old man had extensor tenosynovitis at both wrists and a bilateral tenosynovitis of the extensors at both ankle. Methotrexate in both patients and etanercept in one of them were not effective. Polymerase chain reaction testing revealed Tropheryma whipplei on feces, bursitis and articular fluid samples. Duodenal biopsy proved to be normal. Doxycycline and hydroxychloroquine were rapidly effective. Chronic bursitis and tenosynovitis must be added to the list of rheumatologic manifestations that may evoke the diagnosis of Whipple disease.

Identifiants

pubmed: 32007648
pii: S1297-319X(20)30015-4
doi: 10.1016/j.jbspin.2020.01.010
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

481-482

Informations de copyright

Copyright © 2020 Société française de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.

Auteurs

Jean-Jacques Dubost (JJ)

Department of Rheumatology, CHU Clermont ferrand, 58 rue Montalembert, 63003 Clermont Ferrand Cedex 1, France. Electronic address: jjdubost@chu-clermontferrand.fr.

Marion Couderc (M)

Department of Rheumatology, CHU Clermont ferrand, 58 rue Montalembert, 63003 Clermont Ferrand Cedex 1, France.

Sylvain Mathieu (S)

Department of Rheumatology, CHU Clermont ferrand, 58 rue Montalembert, 63003 Clermont Ferrand Cedex 1, France.

Anne Tournadre (A)

Department of Rheumatology, CHU Clermont ferrand, 58 rue Montalembert, 63003 Clermont Ferrand Cedex 1, France.

Martin Soubrier (M)

Department of Rheumatology, CHU Clermont ferrand, 58 rue Montalembert, 63003 Clermont Ferrand Cedex 1, France.

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