Posttraumatic stress disorder symptom trajectories within the first year following emergency department admissions: pooled results from the International Consortium to predict PTSD.
Latent class growth analysis
posttraumatic stress
resilience
traumatic injuries
Journal
Psychological medicine
ISSN: 1469-8978
Titre abrégé: Psychol Med
Pays: England
ID NLM: 1254142
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
pubmed:
6
2
2020
medline:
1
12
2021
entrez:
4
2
2020
Statut:
ppublish
Résumé
Research exploring the longitudinal course of posttraumatic stress disorder (PTSD) symptoms has documented four modal trajectories (low, remitting, high, and delayed), with proportions varying across studies. Heterogeneity could be due to differences in trauma types and patient demographic characteristics. This analysis pooled data from six longitudinal studies of adult survivors of civilian-related injuries admitted to general hospital emergency departments (EDs) in six countries (pooled N = 3083). Each study included at least three assessments of the clinician-administered PTSD scale in the first post-trauma year. Latent class growth analysis determined the proportion of participants exhibiting various PTSD symptom trajectories within and across the datasets. Multinomial logistic regression analyses examined demographic characteristics, type of event leading to the injury, and trauma history as predictors of trajectories differentiated by their initial severity and course. Five trajectories were found across the datasets: Low (64.5%), Remitting (16.9%), Moderate (6.7%), High (6.5%), and Delayed (5.5%). Female gender, non-white race, prior interpersonal trauma, and assaultive injuries were associated with increased risk for initial PTSD reactions. Female gender and assaultive injuries were associated with risk for membership in the Delayed (v. Low) trajectory, and lower education, prior interpersonal trauma, and assaultive injuries with risk for membership in the High (v. Remitting) trajectory. The results suggest that over 30% of civilian-related injury survivors admitted to EDs experience moderate-to-high levels of PTSD symptoms within the first post-trauma year, with those reporting assaultive violence at increased risk of both immediate and longer-term symptoms.
Sections du résumé
BACKGROUND
Research exploring the longitudinal course of posttraumatic stress disorder (PTSD) symptoms has documented four modal trajectories (low, remitting, high, and delayed), with proportions varying across studies. Heterogeneity could be due to differences in trauma types and patient demographic characteristics.
METHODS
This analysis pooled data from six longitudinal studies of adult survivors of civilian-related injuries admitted to general hospital emergency departments (EDs) in six countries (pooled N = 3083). Each study included at least three assessments of the clinician-administered PTSD scale in the first post-trauma year. Latent class growth analysis determined the proportion of participants exhibiting various PTSD symptom trajectories within and across the datasets. Multinomial logistic regression analyses examined demographic characteristics, type of event leading to the injury, and trauma history as predictors of trajectories differentiated by their initial severity and course.
RESULTS
Five trajectories were found across the datasets: Low (64.5%), Remitting (16.9%), Moderate (6.7%), High (6.5%), and Delayed (5.5%). Female gender, non-white race, prior interpersonal trauma, and assaultive injuries were associated with increased risk for initial PTSD reactions. Female gender and assaultive injuries were associated with risk for membership in the Delayed (v. Low) trajectory, and lower education, prior interpersonal trauma, and assaultive injuries with risk for membership in the High (v. Remitting) trajectory.
CONCLUSIONS
The results suggest that over 30% of civilian-related injury survivors admitted to EDs experience moderate-to-high levels of PTSD symptoms within the first post-trauma year, with those reporting assaultive violence at increased risk of both immediate and longer-term symptoms.
Identifiants
pubmed: 32008580
doi: 10.1017/S0033291719004008
pii: S0033291719004008
pmc: PMC8318129
mid: NIHMS1714468
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1129-1139Subventions
Organisme : NIMH NIH HHS
ID : R01 MH101227
Pays : United States
Références
J Trauma Stress. 2012 Aug;25(4):469-74
pubmed: 22807251
Arch Gen Psychiatry. 1995 Dec;52(12):1048-60
pubmed: 7492257
J Affect Disord. 2013 Mar 20;146(1):71-8
pubmed: 22974469
Clin Psychol Rev. 2018 Jul;63:41-55
pubmed: 29902711
Br J Psychiatry. 2008 May;192(5):376-83
pubmed: 18450664
Psychol Sci. 2012 Dec;23(12):1557-65
pubmed: 23129059
Soc Psychiatry Psychiatr Epidemiol. 2009 Apr;44(4):333-40
pubmed: 18818856
J Anxiety Disord. 2003;17(2):149-64
pubmed: 12614659
J Clin Psychol. 1994 May;50(3):325-40
pubmed: 8071438
J Am Acad Child Adolesc Psychiatry. 2013 Aug;52(8):815-830.e14
pubmed: 23880492
J Abnorm Psychol. 2015 Feb;124(1):155-71
pubmed: 25419860
Br J Psychiatry. 2015 May;206(5):417-23
pubmed: 25657356
Psychoneuroendocrinology. 2014 Jul;45:179-86
pubmed: 24845188
Depress Anxiety. 2016 Jul;33(7):584-91
pubmed: 26740305
J Child Psychol Psychiatry. 2013 Apr;54(4):378-401
pubmed: 23215790
Psychol Med. 2014 Jan;44(1):205-19
pubmed: 23551932
Arch Gen Psychiatry. 2012 Feb;69(2):166-76
pubmed: 21969418
Psychol Med. 2015 Oct;45(13):2885-96
pubmed: 25990926
J Trauma Stress. 2017 Feb;30(1):45-53
pubmed: 28103415
Eur J Psychotraumatol. 2017 Oct 27;8(sup5):1353383
pubmed: 29075426
Eur J Psychotraumatol. 2018 Jun 14;9(1):1476442
pubmed: 29938009
J Trauma Stress. 2015 Feb;28(1):73-8
pubmed: 25630586
Rehabil Psychol. 2010 Feb;55(1):1-11
pubmed: 20175629
Psychol Bull. 2007 Mar;133(2):183-204
pubmed: 17338596
J Trauma Stress. 2010 Jun;23(3):331-9
pubmed: 20564365
J Clin Psychiatry. 2008 Jun;69(6):923-9
pubmed: 18422396
J Trauma Stress. 2011 Jun;24(3):334-41
pubmed: 21594899
Psychiatry Res. 2012 May 15;197(1-2):128-34
pubmed: 22464047
Eur J Psychotraumatol. 2015 Mar 02;6:27503
pubmed: 25735412
Am J Community Psychol. 2014 Mar;53(1-2):159-72
pubmed: 24469249
Soc Sci Med. 2009 Jun;68(12):2190-8
pubmed: 19403217
J Psychiatr Res. 2013 Apr;47(4):520-6
pubmed: 23290559
PLoS One. 2013 Aug 22;8(8):e70084
pubmed: 23990895
J Trauma. 2011 Dec;71(6):1808-15
pubmed: 21841510
Rehabil Psychol. 2012 Aug;57(3):236-47
pubmed: 22946611
Psychol Trauma. 2017 Mar;9(2):138-146
pubmed: 27845522
J Trauma Stress. 1995 Jan;8(1):75-90
pubmed: 7712061