The efficacy of Ultra-High Frequency Ultrasonography in the diagnosis of intraoral lesions.


Journal

Oral surgery, oral medicine, oral pathology and oral radiology
ISSN: 2212-4411
Titre abrégé: Oral Surg Oral Med Oral Pathol Oral Radiol
Pays: United States
ID NLM: 101576782

Informations de publication

Date de publication:
Apr 2020
Historique:
received: 04 05 2019
revised: 07 09 2019
accepted: 21 09 2019
pubmed: 6 2 2020
medline: 28 8 2020
entrez: 4 2 2020
Statut: ppublish

Résumé

The aim of the present study was to evaluate the diagnostic efficacy of ultra-high frequency ultrasound (UHFUS) imaging of intraoral soft tissue lesions. The study included 160 patients presenting with oral soft tissue lesions classified into 4 categories: autoimmune diseases, mucosal growths, potentially (pre)malignant lesions, and oral cancer. Each lesion was evaluated by means of intraoral UHFUS, through B-mode and C-mode acquisitions of the area of interest. The UHFUS findings were compared with the histopathologic findings. All values for sensitivity, specificity, and negative predictive value exceeded 90%. Sensitivity was perfect (100%) for mucosal growths and oral cancer. Specificity was almost perfect for all 4 categories of lesions, ranging from 97% to 99%. Values for positive predictive value ranged from 83% to 99%. UHFUS was beneficial in imaging the oral mucosa and the superficial aspects of the underlying soft tissue in detail because of the high spatial resolution of the technique. Consistent patterns were recognized for different categories of lesions. UHFUS holds the promise of being a valuable support to the clinician in terms of diagnosis, treatment, and follow-up of oral lesions.

Identifiants

pubmed: 32009004
pii: S2212-4403(19)31498-1
doi: 10.1016/j.oooo.2019.09.012
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

401-410

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Rossana Izzetti (R)

Department of Translational Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy. Electronic address: rossana.izzetti@med.unipi.it.

Saverio Vitali (S)

Diagnostic and Interventional Imaging, University Hospital of Pisa, Pisa, Italy.

Giacomo Aringhieri (G)

Diagnostic and Interventional Imaging, University Hospital of Pisa, Pisa, Italy.

Davide Caramella (D)

Diagnostic and Interventional Imaging, University Hospital of Pisa, Pisa, Italy.

Marco Nisi (M)

Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.

Teresa Oranges (T)

Department of Translational Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

Valentina Dini (V)

Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

Filippo Graziani (F)

Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.

Mario Gabriele (M)

Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.

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Classifications MeSH