Vascular Endothelial Growth Factor-121 Administration Mitigates Halogen Inhalation-Induced Pulmonary Injury and Fetal Growth Restriction in Pregnant Mice.

Animals Bromine Disease Models, Animal Female Fetal Development / drug effects Fetal Growth Retardation / blood Injections, Subcutaneous Lung / drug effects Mice, Inbred C57BL Placenta / drug effects Placentation / drug effects Pregnancy Pulmonary Edema / blood Signal Transduction Vascular Endothelial Growth Factor A / administration & dosage Vascular Endothelial Growth Factor Receptor-1 / blood
hemodynamics lung edema preeclampsia pregnancy vascular biology

Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
04 02 2020
Historique:
entrez: 4 2 2020
pubmed: 6 2 2020
medline: 15 12 2020
Statut: ppublish

Résumé

Background Circulating levels of sFLT-1 (soluble fms-like tyrosine kinase 1), the extracellular domain of vascular endothelial growth factor (VEGF) receptor 1, and its ratio to levels of placental growth factor are markers of the occurrence and severity of preeclampsia. Methods and Results C57BL/6 pregnant mice on embryonic day 14.5 (E14.5), male, and non-pregnant female mice were exposed to air or to Br

Identifiants

DOI: 10.1161/JAHA.119.013238 PMID: 32009528 PMC: PMC7033856
pubmed: 32009528
doi: 10.1161/JAHA.119.013238
pmc: PMC7033856
doi:

Substances chimiques

Vascular Endothelial Growth Factor A 0
vascular endothelial growth factor A, mouse 0
Flt1 protein, mouse EC 2.7.10.1
Vascular Endothelial Growth Factor Receptor-1 EC 2.7.10.1
Bromine SBV4XY874G

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

e013238

Subventions

Organisme : NIEHS NIH HHS
ID : U01 ES026458
Pays : United States
Organisme : NIEHS NIH HHS
ID : U01 ES027697
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL129948
Pays : United States
Organisme : NHLBI NIH HHS
ID : T32 HL007918
Pays : United States

Références

J Lipid Res. 2016 Aug;57(8):1529-40
pubmed: 27324796
Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1781-7
pubmed: 21890691
Am J Reprod Immunol. 2015 Apr;73(4):330-40
pubmed: 25271148
Mediators Inflamm. 2016;2016:3027363
pubmed: 27799724
JCI Insight. 2018 Nov 2;3(21):
pubmed: 30385726
Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H541-50
pubmed: 18055511
Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H212-H223
pubmed: 30379573
Respir Res. 2001;2(6):353-64
pubmed: 11737935
J Lipid Res. 2018 Apr;59(4):696-705
pubmed: 29444934
J Med Invest. 2018;65(1.2):64-68
pubmed: 29593196
Am J Obstet Gynecol. 2012 Jan;206(1):58.e1-8
pubmed: 22000672
Int J Epidemiol. 1988 Mar;17(1):148-52
pubmed: 3384533
Am J Physiol Heart Circ Physiol. 2010 Jan;298(1):H189-93
pubmed: 19915174
Toxicol Lett. 2019 Sep 15;312:204-213
pubmed: 31047999
J Cell Biol. 2004 Oct 25;167(2):223-9
pubmed: 15504909
J Appl Physiol (1985). 2005 May;98(5):1626-9
pubmed: 15649874
N Engl J Med. 2004 Feb 12;350(7):672-83
pubmed: 14764923
Nat Cell Biol. 2006 Nov;8(11):1223-34
pubmed: 17060906
Hypertension. 2013 May;61(5):1103-10
pubmed: 23460290
Reprod Sci. 2014 Jan;21(1):138-45
pubmed: 23749761
Mol Med. 2001 Apr;7(4):240-6
pubmed: 11471568
Am J Physiol Regul Integr Comp Physiol. 2013 Jan 15;304(2):R130-5
pubmed: 23193111
Disaster Med Public Health Prep. 2014 Oct;8(5):411-6
pubmed: 25225966
BMC Bioinformatics. 2006 Mar 09;7:123
pubmed: 16526949
Comp Biochem Physiol A Mol Integr Physiol. 2001 May;129(1):287-94
pubmed: 11369552
Thorax. 2003 Apr;58(4):328-32
pubmed: 12668796
Kidney Int. 2005 Oct;68(4):1648-59
pubmed: 16164642
Respir Physiol Neurobiol. 2011 Mar 15;175(3):316-21
pubmed: 21185407
Int J Environ Health Res. 2016;26(1):58-74
pubmed: 25772143
J Am Soc Nephrol. 2012 Apr;23(4):652-60
pubmed: 22282588
Ann Am Thorac Soc. 2016 Mar;13(3):356-63
pubmed: 26695511
Hypertension. 2017 Aug;70(2):390-400
pubmed: 28607126
J Am Heart Assoc. 2020 Feb 4;9(3):e013238
pubmed: 32009528
Obstet Gynecol. 2013 Nov;122(5):1122-1131
pubmed: 24150027
Occup Environ Med. 2001 Jun;58(6):399-404
pubmed: 11351056
Hypertension. 2010 Feb;55(2):380-5
pubmed: 20026764
PLoS One. 2014 Mar 14;9(3):e91897
pubmed: 24632840
Am J Obstet Gynecol. 2007 Apr;196(4):396.e1-7; discussion 396.e7
pubmed: 17403433
Ultrasound Obstet Gynecol. 2016 Mar;47(3):324-31
pubmed: 26387758
Am J Physiol Lung Cell Mol Physiol. 2018 May 1;314(5):L808-L821
pubmed: 29368549

Auteurs

Dylan R Addis (DR)

Division of Cardiothoracic Anesthesiology Department of Anesthesiology and Perioperative Medicine University of Alabama at Birmingham Birmingham AL USA.
Division of Molecular and Translational Biomedicine Department of Anesthesiology and Perioperative Medicine University of Alabama at Birmingham Birmingham AL USA.
UAB Comprehensive Cardiovascular Center University of Alabama at Birmingham Birmingham AL USA.
University of Alabama School of Medicine Birmingham AL USA.

James A Lambert (JA)

Division of Molecular and Translational Biomedicine Department of Anesthesiology and Perioperative Medicine University of Alabama at Birmingham Birmingham AL USA.
Graduate Biomedical Sciences Biochemistry, Structural and Stem Cell Biology Theme University of Alabama at Birmingham Birmingham AL USA.
University of Alabama School of Medicine Birmingham AL USA.

Changchun Ren (C)

Department of Pediatrics Division of Neonatology University of Alabama at Birmingham Birmingham AL USA.
University of Alabama School of Medicine Birmingham AL USA.

Stephen Doran (S)

Division of Molecular and Translational Biomedicine Department of Anesthesiology and Perioperative Medicine University of Alabama at Birmingham Birmingham AL USA.
University of Alabama School of Medicine Birmingham AL USA.

Saurabh Aggarwal (S)

Division of Molecular and Translational Biomedicine Department of Anesthesiology and Perioperative Medicine University of Alabama at Birmingham Birmingham AL USA.
University of Alabama School of Medicine Birmingham AL USA.

Tamas Jilling (T)

Department of Pediatrics Division of Neonatology University of Alabama at Birmingham Birmingham AL USA.
University of Alabama School of Medicine Birmingham AL USA.

Sadis Matalon (S)

Division of Molecular and Translational Biomedicine Department of Anesthesiology and Perioperative Medicine University of Alabama at Birmingham Birmingham AL USA.
UAB Comprehensive Cardiovascular Center University of Alabama at Birmingham Birmingham AL USA.
University of Alabama School of Medicine Birmingham AL USA.

Articles similaires

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Meal Timing and Anthropometric and Metabolic Outcomes: A Systematic Review and Meta-Analysis.

Hiu Yee Liu, Ashley A Eso, Nathan Cook et al.
1.00
Humans Meals Time Factors Female Adult

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Produits chimiques inorganiques › Éléments › Halogènes › Brome › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Développement embryonnaire et foetal › Développement foetal › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Troubles de la croissance › Retard de croissance intra-utérin › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Voies d'administration de substances chimiques et des médicaments › Injections › Injections sous-cutanées › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Appareil respiratoire › Poumon › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Structures de l'embryon › Placenta › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Placentation › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Maladies pulmonaires › Oedème pulmonaire › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Protéines angiogéniques › Facteurs de croissance endothéliale vasculaire › Facteur de croissance endothéliale vasculaire de type A › Vascular Endothelial Growth Factor-121...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteur facteur croissance › Récepteurs aux facteurs de croissance endothéliale vasculaire › Récepteur-1 au facteur croissance endothéliale vasculaire › Vascular Endothelial Growth Factor-121...