VARIATIONS OF ADIPOKINE PROFILE IN PATIENTS DIAGNOSED WITH RECTAL CARCINOMA.
adipokines
adiponectin
leptin
rectal carcinoma
Journal
Acta endocrinologica (Bucharest, Romania : 2005)
ISSN: 1841-0987
Titre abrégé: Acta Endocrinol (Buchar)
Pays: Romania
ID NLM: 101269720
Informations de publication
Date de publication:
Historique:
entrez:
4
2
2020
pubmed:
6
2
2020
medline:
6
2
2020
Statut:
ppublish
Résumé
Adipokine secretion is influenced by various disease conditions. We wanted to check the impact of rectal carcinoma (RC) on adipokine profile. We evaluated serum leptin and adiponectin levels in 24 RC patients (12 males and 12 females) as well as in the same number of age, sex and weight-matched healthy controls. Adipokines were oppositely correlated with body weight (BW) in controls and RC patients. Women had higher adipokine levels than men. Healthy controls had higher leptin (37.6.±7.8 Adipokine profiles of patients with RC differ from the healthy population, possibly reflecting an adaptation to the disease rather than a triggering factor. These differences may find clinical applications for the prognosis of disease evolution.
Sections du résumé
BACKGROUND
BACKGROUND
Adipokine secretion is influenced by various disease conditions.
PURPOSE
OBJECTIVE
We wanted to check the impact of rectal carcinoma (RC) on adipokine profile.
PATIENTS AND METHODS
METHODS
We evaluated serum leptin and adiponectin levels in 24 RC patients (12 males and 12 females) as well as in the same number of age, sex and weight-matched healthy controls.
RESULTS
RESULTS
Adipokines were oppositely correlated with body weight (BW) in controls and RC patients. Women had higher adipokine levels than men. Healthy controls had higher leptin (37.6.±7.8
CONCLUSION
CONCLUSIONS
Adipokine profiles of patients with RC differ from the healthy population, possibly reflecting an adaptation to the disease rather than a triggering factor. These differences may find clinical applications for the prognosis of disease evolution.
Identifiants
pubmed: 32010365
doi: 10.4183/aeb.2019.407
pii: aeb.2019.407
pmc: PMC6992412
doi:
Types de publication
Journal Article
Langues
eng
Pagination
407-409Informations de copyright
©by Acta Endocrinologica Foundation.
Déclaration de conflit d'intérêts
The authors declare that they have no conflict of interest.
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