Tumor necrosis factor receptor family costimulation increases regulatory T-cell activation and function via NF-κB.

Animals Lymphocyte Activation Mice Mice, Knockout NF-kappa B / genetics Receptors, Tumor Necrosis Factor / genetics Signal Transduction / genetics T-Lymphocytes, Regulatory / cytology
Autoimmunity Costimulation NF-κB Regulatory T cells TNF receptor family

Journal

European journal of immunology
ISSN: 1521-4141
Titre abrégé: Eur J Immunol
Pays: Germany
ID NLM: 1273201

Informations de publication

Date de publication:
07 2020
Historique:
received: 06 09 2019
revised: 10 12 2019
accepted: 30 01 2020
pubmed: 6 2 2020
medline: 15 12 2020
entrez: 4 2 2020
Statut: ppublish

Résumé

Several drugs targeting members of the TNF superfamily or TNF receptor superfamily (TNFRSF) are widely used in medicine or are currently being tested in therapeutic trials. However, their mechanism of action remains poorly understood. Here, we explored the effects of TNFRSF co-stimulation on murine Foxp3

Identifiants

DOI: 10.1002/eji.201948393 PMID: 32012260 PMC: PMC7383872
pubmed: 32012260
doi: 10.1002/eji.201948393
pmc: PMC7383872
doi:

Substances chimiques

NF-kappa B 0
Receptors, Tumor Necrosis Factor 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

972-985

Subventions

Organisme : European Union's
ID : H2020
Pays : International
Organisme : ENLIGHT-TEN
ID : 675395
Pays : International
Organisme : ENLIGHT-TEN program
Pays : International
Organisme : Agence Nationale de la Recherche
ID : ANR-15-CE15-0015-01
Pays : International
Organisme : Agence Nationale de la Recherche
ID : ANR-17-CE15-0030-01
Pays : International
Organisme : Deutsche Forschungsgemeinschaft
ID : 324392634
Pays : International
Organisme : Fondation pour la Recherche Médicale
Pays : International
Organisme : European Commission
ID : 675395
Pays : International

Informations de copyright

© 2020 The Authors. European Journal of Immunology published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Références

Immunity. 2008 Apr;28(4):546-58
pubmed: 18387831
Annu Rev Immunol. 2012;30:531-64
pubmed: 22224781
Immunity. 2005 May;22(5):621-31
pubmed: 15894279
Sci Rep. 2018 Aug 13;8(1):12079
pubmed: 30104686
FEBS Lett. 2017 Sep;591(17):2543-2555
pubmed: 28686297
Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14794-9
pubmed: 25267645
J Exp Med. 2016 Jun 27;213(7):1241-53
pubmed: 27270893
Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10672-E10681
pubmed: 30348759
Front Immunol. 2013 Jun 07;4:139
pubmed: 23760533
Front Immunol. 2019 Oct 30;10:2487
pubmed: 31749798
J Immunol. 2004 Oct 15;173(8):5008-20
pubmed: 15470044
J Clin Invest. 2010 Oct;120(10):3629-40
pubmed: 20890040
Elife. 2015 Oct 28;4:e07571
pubmed: 26510014
Cell Rep. 2017 Sep 19;20(12):2906-2920
pubmed: 28889989
J Exp Med. 2013 Aug 26;210(9):1685-93
pubmed: 23897982
Semin Cancer Biol. 2018 Oct;52(Pt 2):39-52
pubmed: 28987965
J Exp Med. 2018 Apr 2;215(4):1091-1100
pubmed: 29511066
J Immunol. 2008 Feb 1;180(3):1565-75
pubmed: 18209052
J Immunol. 2004 Mar 15;172(6):3580-9
pubmed: 15004159
J Biol Chem. 2012 May 18;287(21):17100-8
pubmed: 22461627
J Immunol. 2007 Jul 1;179(1):154-61
pubmed: 17579033
J Immunol. 2007 Aug 1;179(3):1427-30
pubmed: 17641007
Immunol Rev. 2008 Jun;223:371-90
pubmed: 18613848
Immunity. 2016 Nov 15;45(5):1122-1134
pubmed: 27851913
Immunity. 2018 Nov 20;49(5):958-970.e7
pubmed: 30446386
Mucosal Immunol. 2011 Mar;4(2):186-96
pubmed: 20962771
Nat Rev Rheumatol. 2017 Apr;13(4):217-233
pubmed: 28275260
Annu Rev Immunol. 2018 Apr 26;36:755-781
pubmed: 29677472
Immunotherapy. 2015;7(11):1169-86
pubmed: 26567614
Cancer Res. 2006 Jul 15;66(14):7276-84
pubmed: 16849577
Nat Commun. 2013;4:2209
pubmed: 23900386
Immunol Cell Biol. 2014 Jul;92(6):475-80
pubmed: 24732076
Eur J Immunol. 2011 Dec;41(12):3615-26
pubmed: 22229156
Eur J Immunol. 2010 Oct;40(10):2902-13
pubmed: 20806292
Cancer Immunol Res. 2015 Feb;3(2):149-60
pubmed: 25387892
BMC Bioinformatics. 2011 Aug 04;12:323
pubmed: 21816040
Nat Med. 2016 Jan;22(1):16-7
pubmed: 26735402
Cell. 2016 Nov 3;167(4):1067-1078.e16
pubmed: 27773482
Eur J Immunol. 2005 Apr;35(4):1257-66
pubmed: 15761847
J Immunol. 2005 Aug 1;175(3):1651-7
pubmed: 16034105
Bioinformatics. 2013 Jan 1;29(1):15-21
pubmed: 23104886
J Immunol. 2009 Oct 15;183(8):4853-7
pubmed: 19786544
J Immunol. 2002 Feb 1;168(3):1457-65
pubmed: 11801689
J Exp Med. 2010 Aug 30;207(9):1871-8
pubmed: 20679400
Eur J Immunol. 2013 Sep;43(9):2421-9
pubmed: 23722868
J Exp Med. 2016 Aug 22;213(9):1881-900
pubmed: 27526711
Nat Immunol. 2018 Mar;19(3):291-301
pubmed: 29434354
Cytokine. 2006 Jun;34(5-6):233-42
pubmed: 16899371
Eur J Immunol. 2019 Oct;49(10):1457-1973
pubmed: 31633216
Nat Rev Drug Discov. 2013 Feb;12(2):147-68
pubmed: 23334208
Diabetes. 2007 Jan;56(1):186-96
pubmed: 17192481
J Immunol. 2010 Jul 1;185(1):174-82
pubmed: 20525892
J Exp Med. 2008 Apr 14;205(4):825-39
pubmed: 18362171
J Clin Invest. 2010 Dec;120(12):4558-68
pubmed: 21099113
Blood. 2005 Apr 1;105(7):2845-51
pubmed: 15591118
J Immunol. 2010 Apr 1;184(7):3570-81
pubmed: 20181891
J Immunol. 2004 Aug 15;173(4):2428-34
pubmed: 15294956

Auteurs

Martina Lubrano di Ricco (M)

Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Paris, France.

Emilie Ronin (E)

Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Paris, France.

Davi Collares (D)

Université Paris Descartes, Sorbonne Paris Cité, Laboratoire NF-κB, Différenciation et Cancer, Paris, France.

Jordane Divoux (J)

Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Paris, France.

Sylvie Grégoire (S)

Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Paris, France.

Harald Wajant (H)

Division Molecular Internal Medicine, Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.

Tomás Gomes (T)

Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.

Yenkel Grinberg-Bleyer (Y)

Centre de Recherche en Cancérologie de Lyon, UMR INSERM 1052, CNRS 5286, Université Claude Bernard Lyon 1, Labex DEVweCAN, Centre Léon Bérard, Lyon, France.

Véronique Baud (V)

Université Paris Descartes, Sorbonne Paris Cité, Laboratoire NF-κB, Différenciation et Cancer, Paris, France.

Gilles Marodon (G)

Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Paris, France.
ORCID: 0000-0003-4889-6785

Benoît L Salomon (BL)

Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Paris, France.
ORCID: 0000-0001-9673-5578

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Tumor necrosis factor receptor family...
questionsmedicales.fr › Phénomènes du système immunitaire › Activation des lymphocytes › Tumor necrosis factor receptor family...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Tumor necrosis factor receptor family...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › Tumor necrosis factor receptor family...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteur de transcription NF-kappa B › Tumor necrosis factor receptor family...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux cytokines › Récepteurs aux facteurs de nécrose tumorale › Tumor necrosis factor receptor family...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Tumor necrosis factor receptor family...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T régulateurs › Tumor necrosis factor receptor family...